ID   PSTA1_MYCTO             Reviewed;         304 AA.
AC   P9WG10; L0T7X9; O86345; Q50795;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Phosphate transport system permease protein PstA 1;
GN   Name=pstA1; OrderedLocusNames=MT0957;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       phosphate; probably responsible for the translocation of the substrate
CC       across the membrane. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. CysTW subfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE000516; AAK45204.1; -; Genomic_DNA.
DR   PIR; B70584; B70584.
DR   RefSeq; WP_003898651.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WG10; -.
DR   SMR; P9WG10; -.
DR   EnsemblBacteria; AAK45204; AAK45204; MT0957.
DR   KEGG; mtc:MT0957; -.
DR   PATRIC; fig|83331.31.peg.1027; -.
DR   HOGENOM; CLU_033621_2_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0035435; P:phosphate ion transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   InterPro; IPR005672; Phosphate_PstA.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   TIGRFAMs; TIGR00974; 3a0107s02c; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Phosphate transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..304
FT                   /note="Phosphate transport system permease protein PstA 1"
FT                   /id="PRO_0000428443"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        155..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        276..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          89..297
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   304 AA;  32988 MW;  0D4A080694343D2A CRC64;
     MSPSTSIEAL DQPVKPVVFR PLTLRRRIKN SVATTFFFTS FVVALIPLVW LLWVVIARGW
     FAVTRSGWWT HSLRGVLPEQ FAGGVYHALY GTLVQAGVAA VLAVPLGLMT AVYLVEYGTG
     RMSRVTTFTV DVLAGVPSIV AALFVFSLWI ATLGFQQSAF AVALALVLLM LPVVVRAGEE
     MLRLVPDELR EASYALGVPK WKTIVRIVAP IAMPGIVSGI LLSIARVVGE TAPVLVLVGY
     SHSINLDVFH GNMASLPLLI YTELTNPEHA GFLRVWGAAL TLIIVVATIN LAAAMIRFVA
     TRRR