PSTA_MYCGE
ID PSTA_MYCGE Reviewed; 654 AA.
AC P47651;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Phosphate transport system permease protein PstA homolog;
GN Name=pstA; OrderedLocusNames=MG411;
OS Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS (Mycoplasmoides genitalium).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=243273;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT "The minimal gene complement of Mycoplasma genitalium.";
RL Science 270:397-403(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 136-211.
RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL J. Bacteriol. 175:7918-7930(1993).
CC -!- FUNCTION: Could be part of a binding-protein-dependent transport system
CC for phosphate; probably responsible for the translocation of the
CC substrate across the membrane. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. CysTW subfamily. {ECO:0000305}.
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DR EMBL; L43967; AAC71639.1; -; Genomic_DNA.
DR EMBL; U01746; AAD10559.1; -; Genomic_DNA.
DR PIR; E64245; E64245.
DR RefSeq; WP_010869471.1; NC_000908.2.
DR AlphaFoldDB; P47651; -.
DR STRING; 243273.MG_411; -.
DR EnsemblBacteria; AAC71639; AAC71639; MG_411.
DR KEGG; mge:MG_411; -.
DR eggNOG; COG0573; Bacteria.
DR eggNOG; COG0581; Bacteria.
DR HOGENOM; CLU_023674_0_0_14; -.
DR OMA; INIALEM; -.
DR OrthoDB; 1763210at2; -.
DR BioCyc; MGEN243273:G1GJ2-508-MON; -.
DR Proteomes; UP000000807; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0035435; P:phosphate ion transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 2.
DR Gene3D; 1.10.3720.10; -; 2.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR InterPro; IPR005672; Phosphate_PstA.
DR Pfam; PF00528; BPD_transp_1; 2.
DR SUPFAM; SSF161098; SSF161098; 2.
DR TIGRFAMs; TIGR00974; 3a0107s02c; 1.
DR PROSITE; PS50928; ABC_TM1; 2.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Phosphate transport; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..654
FT /note="Phosphate transport system permease protein PstA
FT homolog"
FT /id="PRO_0000060204"
FT TRANSMEM 22..42
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 266..286
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 303..323
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 368..388
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 417..437
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 453..473
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 486..506
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 535..555
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 613..633
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 70..285
FT /note="ABC transmembrane type-1 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 413..623
FT /note="ABC transmembrane type-1 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 654 AA; 73526 MW; 997BD093F7A907B4 CRC64;
MQKKIKKRLK KENLLRIFSK TLAFLFLVLF ISFFVFLLTE ATKIGPDFAK SLFNLEFNLG
NKQAGIWFPL LVSFIVSIGA LIIASYIGVR TSFFLVYRCK PKIRKKLSLI IDILSGIPSV
IFGLFASQIL SIFFRDILKL PPLSLLNVIA MLSFMIIPIV ISLTTNTLTY VNNDLISVVV
SLGENKTSAI YKIIKKEIKP QLTVILTLAF ARAISETMAV NFVLQSVNYQ EVINNNRFFT
SDLKTLGSVI STFIFSENGD EQINGVLYIF GIIILILVSL LNFFAIWSAN PKTLERYPFL
KKISNFIYQV VWFIPNNISA LFVDLTSTRQ SVKKIKVNNI NERSLFFKER LQSVVWIKLN
YFLKIFQELI CTFLAFGFVL AILLFVFING SVAINNNGST VFSFEADSTG RALVNTLVII
LITITITFPL ALLIAIWLNE YNNSKVVKNV FNFVIDSLSS MPSIIYGLFG LSFFLRVLQL
SAGGANGTSL IAGILTISVV ILLFLIRTCQ QALNNVSWDL RISAFALGIS KREVIFKIVL
PSALKGLIVA LILSINRIIA ETAPFFITSG LSSSNLFHLS LPGQTLTTRI YGQLFSINSN
AISVMLETSL VSVVFLILLI FFSSYLIPSL FLLNKQKWLV IKSKFQSFKL WKRT
