ID   PSTC1_MYCTO             Reviewed;         338 AA.
AC   P9WG06; L0T7Y5; O05867; P0A628; P95303;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Phosphate transport system permease protein PstC 1;
GN   Name=pstC1; Synonyms=pstC; OrderedLocusNames=MT0962;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       phosphate; probably responsible for the translocation of the substrate
CC       across the membrane. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. CysTW subfamily. {ECO:0000305}.
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DR   EMBL; AE000516; AAK45209.1; -; Genomic_DNA.
DR   PIR; G70584; G70584.
DR   RefSeq; WP_003404792.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WG06; -.
DR   EnsemblBacteria; AAK45209; AAK45209; MT0962.
DR   KEGG; mtc:MT0962; -.
DR   PATRIC; fig|83331.31.peg.1032; -.
DR   HOGENOM; CLU_033621_1_3_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   InterPro; IPR011864; Phosphate_PstC.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   TIGRFAMs; TIGR02138; phosphate_pstC; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Phosphate transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..338
FT                   /note="Phosphate transport system permease protein PstC 1"
FT                   /id="PRO_0000428445"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        123..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        232..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        295..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          87..320
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   338 AA;  34793 MW;  10D7BA65D72F7F96 CRC64;
     MLARAGEVGR AGPAIRWLGG IGAVIPLLAL VLVLVVLVIE AMGAIRLNGL HFFTATEWNP
     GNTYGETVVT DGVAHPVGAY YGALPLIVGT LATSAIALII AVPVSVGAAL VIVERLPKRL
     AEAVGIVLEL LAGIPSVVVG LWGAMTFGPF IAHHIAPVIA HNAPDVPVLN YLRGDPGNGE
     GMLVSGLVLA VMVVPIIATT THDLFRQVPV LPREGAIALG MSNWECVRRV TLPWVSSGIV
     GAVVLGLGRA LGETMAVAMV SGAVLGAMPA NIYATMTTIA ATIVSQLDSA MTDSTNFAVK
     TLAEVGLVLM VITLLTNVAA RGMVRRVSRT ALPVGRGI