ID   PSTC2_MYCBO             Reviewed;         324 AA.
AC   P0A631; A0A1R3XWV5; O86344; Q50797; X2BGK2;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Phosphate transport system permease protein PstC 2;
GN   Name=pstC2; OrderedLocusNames=BQ2027_MB0952;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       phosphate; probably responsible for the translocation of the substrate
CC       across the membrane. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. CysTW subfamily. {ECO:0000305}.
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DR   EMBL; LT708304; SIT99550.1; -; Genomic_DNA.
DR   RefSeq; NP_854609.1; NC_002945.3.
DR   RefSeq; WP_003404779.1; NC_002945.4.
DR   AlphaFoldDB; P0A631; -.
DR   EnsemblBacteria; SIT99550; SIT99550; BQ2027_MB0952.
DR   GeneID; 45424895; -.
DR   PATRIC; fig|233413.5.peg.1037; -.
DR   OMA; VIRMSVL; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   InterPro; IPR011864; Phosphate_PstC.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   TIGRFAMs; TIGR02138; phosphate_pstC; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Phosphate transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..324
FT                   /note="Phosphate transport system permease protein PstC 2"
FT                   /id="PRO_0000060216"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        125..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        174..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        237..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        290..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          85..314
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   324 AA;  34262 MW;  0C54657C8A3CEAC5 CRC64;
     MVTEPLTKPA LVAVDMRPAR RGERLFKLAA SAAGSTIVIA ILLIAIFLLV RAVPSLRANH
     ANFFTSTQFD TSDDEQLAFG VRDLFMVTAL SSITALVLAV PVAVGIAVFL THYAPRRLSR
     PFGAMVDLLA AVPSIIFGLW GIFVLAPKLE PIARFLNRNL GWLFLFKQGN VSLAGGGTIF
     TAGIVLSVMI LPIVTSISRE VFRQTPLIQI EAALALGATK WEVVRMTVLP YGRSGVVAAS
     MLGLGRALGE TVAVLVILRS AARPGTWSLF DGGYTFASKI ASAASEFSEP LPTGAYISAG
     FALFVLTFLV NAAARAIAGG KVNG