PSTC_SHIFL
ID PSTC_SHIFL Reviewed; 319 AA.
AC P0AGI0; P07653;
DT 01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1988, sequence version 1.
DT 25-MAY-2022, entry version 97.
DE RecName: Full=Phosphate transport system permease protein PstC;
GN Name=pstC; OrderedLocusNames=SF3728, S4044;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC phosphate; probably responsible for the translocation of the substrate
CC across the membrane. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. CysTW subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAN45174.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE005674; AAN45174.1; ALT_INIT; Genomic_DNA.
DR EMBL; AE014073; AAP19024.1; -; Genomic_DNA.
DR RefSeq; NP_709467.3; NC_004337.2.
DR RefSeq; WP_000741620.1; NZ_WPGW01000131.1.
DR AlphaFoldDB; P0AGI0; -.
DR STRING; 198214.SF3728; -.
DR EnsemblBacteria; AAN45174; AAN45174; SF3728.
DR EnsemblBacteria; AAP19024; AAP19024; S4044.
DR GeneID; 1026124; -.
DR GeneID; 66672373; -.
DR KEGG; sfl:SF3728; -.
DR KEGG; sfx:S4044; -.
DR PATRIC; fig|198214.7.peg.4401; -.
DR HOGENOM; CLU_033621_1_3_6; -.
DR OrthoDB; 1325025at2; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR InterPro; IPR011864; Phosphate_PstC.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR TIGRFAMs; TIGR02138; phosphate_pstC; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Phosphate transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..319
FT /note="Phosphate transport system permease protein PstC"
FT /id="PRO_0000060212"
FT TOPO_DOM 1..24
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 25..44
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 45..74
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 75..94
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 95..117
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 118..137
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 138..167
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 168..187
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 188..232
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 233..252
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 253..283
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 284..303
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 304..319
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 75..305
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT CONFLICT 304..319
FT /note="Missing (in Ref. 2; AAP19024)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 319 AA; 34121 MW; 843F9E811DB62597 CRC64;
MAATKPAFNP PGKKGDIIFS VLVKLAALIV LLMLGGIIVS LIISSWPSIQ KFGLAFLWTK
EWDAPNDIYG ALVPIYGTLV TSFIALLIAV PVSFGIALFL TELAPGWLKR PLGIAIELLA
AIPSIVYGMW GLFIFAPLFA VYFQEPVGNI MSNIPIVGAL FSGPAFGIGI LAAGVILAIM
IIPYIAAVMR DVFEQTPVMM KESAYGIGCT TWEVIWRIVL PFTKNGVIGG IMLGLGRALG
ETMAVTFIIG NTYQLDSASL YMPGNSITSA LANEFAEAES GLHVAALMEL GLILFVITFI
VLAASKFMIM RLAKNEGAR
