PSTS1_STRR6
ID PSTS1_STRR6 Reviewed; 292 AA.
AC Q8DPB1;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=Phosphate-binding protein PstS 1;
DE Short=PBP 1;
DE Flags: Precursor;
GN Name=pstS1; OrderedLocusNames=spr1257;
OS Streptococcus pneumoniae (strain ATCC BAA-255 / R6).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=171101;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-255 / R6;
RX PubMed=11544234; DOI=10.1128/jb.183.19.5709-5717.2001;
RA Hoskins J., Alborn W.E. Jr., Arnold J., Blaszczak L.C., Burgett S.,
RA DeHoff B.S., Estrem S.T., Fritz L., Fu D.-J., Fuller W., Geringer C.,
RA Gilmour R., Glass J.S., Khoja H., Kraft A.R., Lagace R.E., LeBlanc D.J.,
RA Lee L.N., Lefkowitz E.J., Lu J., Matsushima P., McAhren S.M., McHenney M.,
RA McLeaster K., Mundy C.W., Nicas T.I., Norris F.H., O'Gara M., Peery R.B.,
RA Robertson G.T., Rockey P., Sun P.-M., Winkler M.E., Yang Y.,
RA Young-Bellido M., Zhao G., Zook C.A., Baltz R.H., Jaskunas S.R.,
RA Rosteck P.R. Jr., Skatrud P.L., Glass J.I.;
RT "Genome of the bacterium Streptococcus pneumoniae strain R6.";
RL J. Bacteriol. 183:5709-5717(2001).
CC -!- FUNCTION: Part of the ABC transporter complex PstSACB involved in
CC phosphate import. {ECO:0000250}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (PstB),
CC two transmembrane proteins (PstC and PstA) and a solute-binding protein
CC (PstS). {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the PstS family. {ECO:0000305}.
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DR EMBL; AE007317; AAL00061.1; -; Genomic_DNA.
DR PIR; H98028; H98028.
DR RefSeq; NP_358850.1; NC_003098.1.
DR RefSeq; WP_000746338.1; NC_003098.1.
DR PDB; 4EXL; X-ray; 1.70 A; A/B/C/D=28-292.
DR PDBsum; 4EXL; -.
DR AlphaFoldDB; Q8DPB1; -.
DR SMR; Q8DPB1; -.
DR STRING; 171101.spr1257; -.
DR EnsemblBacteria; AAL00061; AAL00061; spr1257.
DR GeneID; 60233188; -.
DR GeneID; 66806516; -.
DR KEGG; spr:spr1257; -.
DR PATRIC; fig|171101.6.peg.1363; -.
DR eggNOG; COG0226; Bacteria.
DR HOGENOM; CLU_026228_5_0_9; -.
DR OMA; FKKKALC; -.
DR Proteomes; UP000000586; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042301; F:phosphate ion binding; IEA:InterPro.
DR GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR024370; PBP_domain.
DR InterPro; IPR011862; Phos-bd.
DR Pfam; PF12849; PBP_like_2; 1.
DR TIGRFAMs; TIGR02136; ptsS_2; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell membrane; Lipoprotein; Membrane; Palmitate;
KW Phosphate transport; Reference proteome; Signal; Transport.
FT SIGNAL 1..18
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 19..292
FT /note="Phosphate-binding protein PstS 1"
FT /id="PRO_0000281672"
FT LIPID 19
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT LIPID 19
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT STRAND 32..37
FT /evidence="ECO:0007829|PDB:4EXL"
FT HELIX 41..55
FT /evidence="ECO:0007829|PDB:4EXL"
FT STRAND 60..66
FT /evidence="ECO:0007829|PDB:4EXL"
FT HELIX 68..76
FT /evidence="ECO:0007829|PDB:4EXL"
FT STRAND 79..87
FT /evidence="ECO:0007829|PDB:4EXL"
FT HELIX 89..91
FT /evidence="ECO:0007829|PDB:4EXL"
FT HELIX 97..99
FT /evidence="ECO:0007829|PDB:4EXL"
FT STRAND 104..114
FT /evidence="ECO:0007829|PDB:4EXL"
FT HELIX 125..132
FT /evidence="ECO:0007829|PDB:4EXL"
FT HELIX 139..141
FT /evidence="ECO:0007829|PDB:4EXL"
FT STRAND 150..154
FT /evidence="ECO:0007829|PDB:4EXL"
FT HELIX 159..167
FT /evidence="ECO:0007829|PDB:4EXL"
FT TURN 168..171
FT /evidence="ECO:0007829|PDB:4EXL"
FT STRAND 178..180
FT /evidence="ECO:0007829|PDB:4EXL"
FT HELIX 183..192
FT /evidence="ECO:0007829|PDB:4EXL"
FT STRAND 196..201
FT /evidence="ECO:0007829|PDB:4EXL"
FT HELIX 202..204
FT /evidence="ECO:0007829|PDB:4EXL"
FT STRAND 209..211
FT /evidence="ECO:0007829|PDB:4EXL"
FT HELIX 221..225
FT /evidence="ECO:0007829|PDB:4EXL"
FT STRAND 232..242
FT /evidence="ECO:0007829|PDB:4EXL"
FT HELIX 245..255
FT /evidence="ECO:0007829|PDB:4EXL"
FT HELIX 257..261
FT /evidence="ECO:0007829|PDB:4EXL"
FT HELIX 263..266
FT /evidence="ECO:0007829|PDB:4EXL"
FT HELIX 272..274
FT /evidence="ECO:0007829|PDB:4EXL"
FT STRAND 276..279
FT /evidence="ECO:0007829|PDB:4EXL"
FT STRAND 285..287
FT /evidence="ECO:0007829|PDB:4EXL"
SQ SEQUENCE 292 AA; 31201 MW; F11AB50A3590485B CRC64;
MKKRKKLALS LIAFWLTACL VGCASWIDRG ESITAVGSTA LQPLVEVAAD EFGTIHVGKT
VNVQGGGSGT GLSQVQSGAV DIGNSDVFAE EKDGIDASAL VDHKVAVAGL ALIVNKEVDV
DNLTTEQLRQ IFIGEVTNWK EVGGKDLPIS VINRAAGSGS RATFDTVIME GQSAMQSQEQ
DSNGAVKSIV SKSPGAISYL SLTYIDDSVK SMKLNGYDLS PENISSNNWP LWSYEHMYTL
GQPNELAAEF LNFVLSDETQ EGIVKGLKYI PIKEMKVEKD AAGTVTVLEG RQ
