ATP11_YEAST
ID ATP11_YEAST Reviewed; 318 AA.
AC P32453; D6W0N0;
DT 01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1993, sequence version 1.
DT 03-AUG-2022, entry version 158.
DE RecName: Full=Protein ATP11, mitochondrial;
DE Flags: Precursor;
GN Name=ATP11; OrderedLocusNames=YNL315C; ORFNames=N0357;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1532796; DOI=10.1016/s0021-9258(18)42529-x;
RA Ackerman S.H., Martin J., Tzagoloff A.;
RT "Characterization of ATP11 and detection of the encoded protein in
RT mitochondria of Saccharomyces cerevisiae.";
RL J. Biol. Chem. 267:7386-7394(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=S288c / FY1676;
RX PubMed=7502583; DOI=10.1002/yea.320111109;
RA Maftahi M., Nicaud J.-M., Levesque H., Gaillardin C.;
RT "Sequencing analysis of a 24.7 kb fragment of yeast chromosome XIV
RT identifies six known genes, a new member of the hexose transporter family
RT and ten new open reading frames.";
RL Yeast 11:1077-1085(1995).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169873;
RA Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K.,
RA Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K.,
RA Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M.,
RA Beinhauer J.D., Boskovic J., Buitrago M.J., Bussereau F., Coster F.,
RA Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F.,
RA Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C.,
RA Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A.,
RA Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H.,
RA Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L.,
RA Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R.,
RA Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D.,
RA Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A.,
RA Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C.,
RA Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F.,
RA Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G.,
RA Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M.,
RA Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its
RT evolutionary implications.";
RL Nature 387:93-98(1997).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [6]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [7]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-109, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ADR376;
RX PubMed=17330950; DOI=10.1021/pr060559j;
RA Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,
RA Elias J.E., Gygi S.P.;
RT "Large-scale phosphorylation analysis of alpha-factor-arrested
RT Saccharomyces cerevisiae.";
RL J. Proteome Res. 6:1190-1197(2007).
RN [8]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19779198; DOI=10.1126/science.1172867;
RA Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT into evolution.";
RL Science 325:1682-1686(2009).
CC -!- FUNCTION: Essential for the assembly of the mitochondrial F1-F0
CC complex. May interact with the alpha and/or beta subunits of F1-ATPase.
CC -!- SUBCELLULAR LOCATION: Mitochondrion.
CC -!- MISCELLANEOUS: Present with 2840 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: Belongs to the ATP11 family. {ECO:0000305}.
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DR EMBL; M87006; AAA34447.1; -; Genomic_DNA.
DR EMBL; Z46259; CAA86381.1; -; Genomic_DNA.
DR EMBL; Z71591; CAA96245.1; -; Genomic_DNA.
DR EMBL; AY693039; AAT93058.1; -; Genomic_DNA.
DR EMBL; BK006947; DAA10246.1; -; Genomic_DNA.
DR PIR; S51297; S51297.
DR RefSeq; NP_014084.1; NM_001183153.1.
DR AlphaFoldDB; P32453; -.
DR SMR; P32453; -.
DR BioGRID; 35524; 327.
DR DIP; DIP-3026N; -.
DR IntAct; P32453; 7.
DR MINT; P32453; -.
DR STRING; 4932.YNL315C; -.
DR iPTMnet; P32453; -.
DR MaxQB; P32453; -.
DR PaxDb; P32453; -.
DR PRIDE; P32453; -.
DR EnsemblFungi; YNL315C_mRNA; YNL315C; YNL315C.
DR GeneID; 855401; -.
DR KEGG; sce:YNL315C; -.
DR SGD; S000005259; ATP11.
DR VEuPathDB; FungiDB:YNL315C; -.
DR eggNOG; KOG3281; Eukaryota.
DR GeneTree; ENSGT00390000012765; -.
DR HOGENOM; CLU_054226_2_0_1; -.
DR InParanoid; P32453; -.
DR OMA; QWGFHPP; -.
DR BioCyc; YEAST:G3O-33302-MON; -.
DR PRO; PR:P32453; -.
DR Proteomes; UP000002311; Chromosome XIV.
DR RNAct; P32453; protein.
DR GO; GO:0005739; C:mitochondrion; IDA:SGD.
DR GO; GO:0051082; F:unfolded protein binding; IDA:SGD.
DR GO; GO:0033615; P:mitochondrial proton-transporting ATP synthase complex assembly; IMP:SGD.
DR GO; GO:0007005; P:mitochondrion organization; IMP:SGD.
DR InterPro; IPR010591; ATP11.
DR PANTHER; PTHR13126; PTHR13126; 1.
DR Pfam; PF06644; ATP11; 1.
PE 1: Evidence at protein level;
KW Mitochondrion; Phosphoprotein; Reference proteome; Transit peptide.
FT TRANSIT 1..?40
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN ?41..318
FT /note="Protein ATP11, mitochondrial"
FT /id="PRO_0000002535"
FT MOD_RES 109
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:17330950"
SQ SEQUENCE 318 AA; 36851 MW; 61109AA4D338F2CD CRC64;
MWRLTRKIGT RIHISNQLSP IFNKAIGTVP VFRFYSSSPE QKYRKKLLEE AQKQGFNSIE
ELKNHLKETI ESKKREFNKI DPLKELEDYQ QKTQMENNNS KHLMTKSRSP LDPSAPKVPF
KTLDSFLDVG KLKDLSKQEV EFLWRARWAQ KDNTLCAVIP VSVYDKMMAN ARNNPIFVLP
LPRQVQSEDA KPNEEQGMEL HYIQWQFVGP QTTHCMMTSL AEYKLHQEFA RPHTTLQFHS
DLVKDKGIVF MNGHVEPDTN VNVQDAQLLL LNVQRFYGAM GEETPVAKQR VQLLRDFSKA
SPGFTVEKLI SLSQSMEN
