ATP12_SCHPO
ID ATP12_SCHPO Reviewed; 291 AA.
AC Q9UT16;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 13-JUN-2012, sequence version 2.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=Protein atp12, mitochondrial;
DE Flags: Precursor;
GN Name=atp12; ORFNames=SPAC9.12c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP REVISION OF GENE MODEL.
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: Essential for the assembly of the mitochondrial F1-F0
CC complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the ATP12 family. {ECO:0000305}.
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DR EMBL; CU329670; CAB57430.2; -; Genomic_DNA.
DR PIR; T39197; T39197.
DR RefSeq; NP_593355.2; NM_001018787.2.
DR AlphaFoldDB; Q9UT16; -.
DR SMR; Q9UT16; -.
DR BioGRID; 279828; 41.
DR STRING; 4896.SPAC9.12c.1; -.
DR MaxQB; Q9UT16; -.
DR PaxDb; Q9UT16; -.
DR EnsemblFungi; SPAC9.12c.1; SPAC9.12c.1:pep; SPAC9.12c.
DR GeneID; 2543406; -.
DR KEGG; spo:SPAC9.12c; -.
DR PomBase; SPAC9.12c; atp12.
DR VEuPathDB; FungiDB:SPAC9.12c; -.
DR eggNOG; KOG3015; Eukaryota.
DR HOGENOM; CLU_047893_1_0_1; -.
DR InParanoid; Q9UT16; -.
DR OMA; DTVLFQY; -.
DR PRO; PR:Q9UT16; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005759; C:mitochondrial matrix; ISO:PomBase.
DR GO; GO:0005739; C:mitochondrion; HDA:PomBase.
DR GO; GO:0051082; F:unfolded protein binding; ISO:PomBase.
DR GO; GO:0033615; P:mitochondrial proton-transporting ATP synthase complex assembly; ISO:PomBase.
DR Gene3D; 1.10.3580.10; -; 1.
DR Gene3D; 3.30.2180.10; -; 1.
DR InterPro; IPR011419; ATP12_ATP_synth-F1-assembly.
DR InterPro; IPR042272; ATP12_ATP_synth-F1-assembly_N.
DR InterPro; IPR023335; ATP12_ortho_dom_sf.
DR PANTHER; PTHR21013; PTHR21013; 1.
DR Pfam; PF07542; ATP12; 1.
PE 3: Inferred from homology;
KW Chaperone; Mitochondrion; Reference proteome; Transit peptide.
FT TRANSIT 1..10
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 11..291
FT /note="Protein atp12, mitochondrial"
FT /id="PRO_0000002420"
SQ SEQUENCE 291 AA; 33600 MW; 7DFD9A69AD5FABE7 CRC64;
MLRSLQFYRL SSKNLLSFKT CYSFYSTKAS SPLPQPSFRR FWKNTATKIQ NGEVLIQLDG
RNLKSPSGKI VKVPKEMELL AHLIALEWDR LPSTSVRQHN LPITSLVSRA IDISQFKKEE
KELLSTQLIR FLDTDTILIY SPETEYEGKL LEEQKENWWP LKETFENKLG VQLSYLDGDA
GIIAHKQTQE THERIRNWLS SLNSWQLAAF ERSVSCCKSF IVSFMILKGY LNSEKAAALT
NLELQYQTNR WGSLEDAHEI DNEDLKNKLA SSAILSRCIE DMHDKSNEHA H
