PSTS_STAEQ
ID PSTS_STAEQ Reviewed; 325 AA.
AC Q5HPF2;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=Phosphate-binding protein PstS;
DE Short=PBP;
DE Flags: Precursor;
GN Name=pstS; OrderedLocusNames=SERP0960;
OS Staphylococcus epidermidis (strain ATCC 35984 / RP62A).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=176279;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35984 / RP62A;
RX PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA Fraser C.M.;
RT "Insights on evolution of virulence and resistance from the complete genome
RT analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT strain.";
RL J. Bacteriol. 187:2426-2438(2005).
CC -!- FUNCTION: Part of the ABC transporter complex PstSACB involved in
CC phosphate import. {ECO:0000250}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (PstB),
CC two transmembrane proteins (PstC and PstA) and a solute-binding protein
CC (PstS). {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the PstS family. {ECO:0000305}.
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DR EMBL; CP000029; AAW54387.1; -; Genomic_DNA.
DR RefSeq; WP_002486097.1; NC_002976.3.
DR AlphaFoldDB; Q5HPF2; -.
DR SMR; Q5HPF2; -.
DR STRING; 176279.SERP0960; -.
DR EnsemblBacteria; AAW54387; AAW54387; SERP0960.
DR KEGG; ser:SERP0960; -.
DR eggNOG; COG0226; Bacteria.
DR HOGENOM; CLU_026228_1_1_9; -.
DR OMA; GTKHGTR; -.
DR OrthoDB; 1222928at2; -.
DR Proteomes; UP000000531; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042301; F:phosphate ion binding; IEA:InterPro.
DR GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR024370; PBP_domain.
DR InterPro; IPR011862; Phos-bd.
DR Pfam; PF12849; PBP_like_2; 1.
DR TIGRFAMs; TIGR02136; ptsS_2; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Phosphate transport;
KW Reference proteome; Signal; Transport.
FT SIGNAL 1..20
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 21..325
FT /note="Phosphate-binding protein PstS"
FT /id="PRO_0000281662"
FT REGION 23..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 21
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT LIPID 21
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ SEQUENCE 325 AA; 35920 MW; 2A2C7A2C4D0303AA CRC64;
MKKWQLVGTT VLGASVLLGA CGGNDGGSGD GKDLKGSAKG EGSSTVAPIV EKLNEKWAKD
HKDAKISSGQ AGTGAGFQKF IAGETDFSDA SRPIKDEEKK KLEDKGIKYH EFKIAQDGVT
IAVNKDNDFV KELTKSQLKD IYSGKAKTWK DVNSSWPDKK INAVSPNSSH GTYDFFEEEV
MDKQDIKAEK NADTNAIVSS VTKNKEGIGY FGYNFYEQNK DKLKEVKIKD DNGKVTEPTK
KTIQNGSYAL SRPLFIYAKD KSLKDNKVMS EFMKFVLEDE GQAAEDAGYV ASPKKTYKSQ
LDDLKDFLDK HQKSDKKDDK TSEDK
