PSY1_SCHPO
ID PSY1_SCHPO Reviewed; 284 AA.
AC Q9USH7;
DT 06-DEC-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 136.
DE RecName: Full=Syntaxin-like protein psy1;
GN Name=psy1; Synonyms=sso1; ORFNames=SPCC825.03c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND SUBCELLULAR LOCATION.
RX PubMed=11739793; DOI=10.1091/mbc.12.12.3955;
RA Nakamura T., Nakamura-Kubo M., Hirata A., Shimoda C.;
RT "The Schizosaccharomyces pombe spo3+ gene is required for assembly of the
RT forespore membrane and genetically interacts with psy1(+)-encoding
RT syntaxin-like protein.";
RL Mol. Biol. Cell 12:3955-3972(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:11739793};
CC Single-pass type IV membrane protein {ECO:0000269|PubMed:11739793}.
CC Prospore membrane {ECO:0000269|PubMed:11739793}. Note=During vegetative
CC growth located at the plasma membrane. As meiosis II is initiated
CC located at the forespore membrane.
CC -!- SIMILARITY: Belongs to the syntaxin family. {ECO:0000305}.
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DR EMBL; CU329672; CAB58411.1; -; Genomic_DNA.
DR PIR; T41624; T41624.
DR RefSeq; NP_588053.1; NM_001023045.2.
DR AlphaFoldDB; Q9USH7; -.
DR SMR; Q9USH7; -.
DR BioGRID; 275943; 11.
DR STRING; 4896.SPCC825.03c.1; -.
DR SwissPalm; Q9USH7; -.
DR MaxQB; Q9USH7; -.
DR PaxDb; Q9USH7; -.
DR EnsemblFungi; SPCC825.03c.1; SPCC825.03c.1:pep; SPCC825.03c.
DR GeneID; 2539377; -.
DR KEGG; spo:SPCC825.03c; -.
DR PomBase; SPCC825.03c; psy1.
DR VEuPathDB; FungiDB:SPCC825.03c; -.
DR eggNOG; KOG0810; Eukaryota.
DR HOGENOM; CLU_042423_0_1_1; -.
DR InParanoid; Q9USH7; -.
DR OMA; RWICFIL; -.
DR PhylomeDB; Q9USH7; -.
DR Reactome; R-SPO-114516; Disinhibition of SNARE formation.
DR Reactome; R-SPO-199992; trans-Golgi Network Vesicle Budding.
DR Reactome; R-SPO-9609523; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane.
DR PRO; PR:Q9USH7; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0032153; C:cell division site; IDA:PomBase.
DR GO; GO:0051286; C:cell tip; IDA:PomBase.
DR GO; GO:0005737; C:cytoplasm; IDA:PomBase.
DR GO; GO:0012505; C:endomembrane system; IBA:GO_Central.
DR GO; GO:0005768; C:endosome; IDA:PomBase.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IDA:PomBase.
DR GO; GO:0044853; C:plasma membrane raft; IDA:PomBase.
DR GO; GO:0005628; C:prospore membrane; IDA:PomBase.
DR GO; GO:0070056; C:prospore membrane leading edge; IDA:PomBase.
DR GO; GO:0070057; C:prospore membrane spindle pole body attachment site; IDA:PomBase.
DR GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR GO; GO:0005484; F:SNAP receptor activity; IBA:GO_Central.
DR GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR GO; GO:0030437; P:ascospore formation; IGI:PomBase.
DR GO; GO:0032120; P:ascospore-type prospore membrane formation; IMP:PomBase.
DR GO; GO:0006887; P:exocytosis; IBA:GO_Central.
DR GO; GO:0006893; P:Golgi to plasma membrane transport; ISO:PomBase.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0048278; P:vesicle docking; IBA:GO_Central.
DR GO; GO:0006906; P:vesicle fusion; IBA:GO_Central.
DR CDD; cd00179; SynN; 1.
DR InterPro; IPR010989; SNARE.
DR InterPro; IPR045242; Syntaxin.
DR InterPro; IPR006012; Syntaxin/epimorphin_CS.
DR InterPro; IPR006011; Syntaxin_N.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR19957; PTHR19957; 1.
DR Pfam; PF05739; SNARE; 1.
DR Pfam; PF00804; Syntaxin; 1.
DR SMART; SM00503; SynN; 1.
DR SMART; SM00397; t_SNARE; 1.
DR SUPFAM; SSF47661; SSF47661; 1.
DR PROSITE; PS00914; SYNTAXIN; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 3: Inferred from homology;
KW Cell membrane; Coiled coil; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..284
FT /note="Syntaxin-like protein psy1"
FT /id="PRO_0000210269"
FT TRANSMEM 260..280
FT /note="Helical; Anchor for type IV membrane protein"
FT /evidence="ECO:0000255"
FT DOMAIN 181..243
FT /note="t-SNARE coiled-coil homology"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00202"
FT COILED 23..57
FT /evidence="ECO:0000255"
SQ SEQUENCE 284 AA; 32550 MW; C7E3AB14A61CB256 CRC64;
MNKANDYTLG VEMIPLSMGE FFEEIDHIRD AIRQIEDNVG RIEMLHQQSL QEIDEANIAA
TTRHLEGYTS DTRRLQTSVQ LAIRSLESQN MQLPPDNDTA TRKTQTEAVK KKFMDQIRHF
LQIEKTYRAQ YEQRMRRQLE IANPRATEDD FQTAINEENG GQVFAQALLR SNRSGEARTA
LREVQERHAD IKRIERTIAE LAQLFQDMAT MVQEQEPMVD KIVTDAVNVR TNMGEGTQHM
DRAIKSARAA RKKKWICFGI CVVIICVIVA VLCGVLIPVL GNRH
