PSY2_ARATH
ID PSY2_ARATH Reviewed; 71 AA.
AC Q8LE92;
DT 03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=Protein PSY2;
DE Contains:
DE RecName: Full=Tyrosine-sulfated glycopeptide 2;
DE Flags: Precursor;
GN Name=PSY2; OrderedLocusNames=At3g47295; ORFNames=T21L8.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP IDENTIFICATION.
RC STRAIN=cv. Columbia;
RX PubMed=17989228; DOI=10.1073/pnas.0706403104;
RA Amano Y., Tsubouchi H., Shinohara H., Ogawa M., Matsubayashi Y.;
RT "Tyrosine-sulfated glycopeptide involved in cellular proliferation and
RT expansion in Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:18333-18338(2007).
CC -!- FUNCTION: Promotes cellular proliferation and expansion. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- PTM: The sulfation and the glycosylation are required for full
CC activity. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the sulfated-peptide plant hormone family.
CC {ECO:0000305}.
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DR EMBL; AL096860; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002686; AEE78262.1; -; Genomic_DNA.
DR EMBL; AK117627; BAC42283.1; -; mRNA.
DR EMBL; BT004922; AAO50455.1; -; mRNA.
DR EMBL; AY085556; AAM67244.1; -; mRNA.
DR RefSeq; NP_566890.1; NM_114597.2.
DR AlphaFoldDB; Q8LE92; -.
DR STRING; 3702.AT3G47295.1; -.
DR PaxDb; Q8LE92; -.
DR PRIDE; Q8LE92; -.
DR EnsemblPlants; AT3G47295.1; AT3G47295.1; AT3G47295.
DR GeneID; 823883; -.
DR Gramene; AT3G47295.1; AT3G47295.1; AT3G47295.
DR KEGG; ath:AT3G47295; -.
DR Araport; AT3G47295; -.
DR TAIR; locus:505006387; AT3G47295.
DR HOGENOM; CLU_197080_1_0_1; -.
DR InParanoid; Q8LE92; -.
DR OMA; LMMTIED; -.
DR OrthoDB; 1615838at2759; -.
DR PRO; PR:Q8LE92; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q8LE92; baseline and differential.
DR Genevisible; Q8LE92; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR InterPro; IPR034430; PSY.
DR PANTHER; PTHR37177; PTHR37177; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Growth factor; Hydroxylation; Reference proteome; Secreted;
KW Signal; Sulfation.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT PROPEP 21..46
FT /evidence="ECO:0000255"
FT /id="PRO_0000365612"
FT PEPTIDE 47..64
FT /note="Tyrosine-sulfated glycopeptide 2"
FT /id="PRO_0000365613"
FT PROPEP 65..71
FT /evidence="ECO:0000255"
FT /id="PRO_0000365614"
FT REGION 50..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 48
FT /note="Sulfotyrosine"
FT /evidence="ECO:0000250"
FT MOD_RES 62
FT /note="4-hydroxyproline"
FT /evidence="ECO:0000250"
FT CARBOHYD 62
FT /note="O-linked (Ara...) hydroxyproline"
FT /evidence="ECO:0000250"
SQ SEQUENCE 71 AA; 7694 MW; 8FA12417B130A27E CRC64;
MSFGTRLLLF LILTLPLVTS SSPNTLHVSG IVKTGTTSRF LMMTIEDYDD PSANTRHDPS
VPTNAKADTT P
