ID   PSY3_ARATH              Reviewed;          71 AA.
AC   Q8S8P7;
DT   03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Protein PSY3;
DE   Contains:
DE     RecName: Full=Tyrosine-sulfated glycopeptide 3;
DE   Flags: Precursor;
GN   Name=PSY3; OrderedLocusNames=At2g29995; ORFNames=F23F1.2;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Shinn P., Chen H., Kim C.J., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   IDENTIFICATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=17989228; DOI=10.1073/pnas.0706403104;
RA   Amano Y., Tsubouchi H., Shinohara H., Ogawa M., Matsubayashi Y.;
RT   "Tyrosine-sulfated glycopeptide involved in cellular proliferation and
RT   expansion in Arabidopsis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:18333-18338(2007).
CC   -!- FUNCTION: Promotes cellular proliferation and expansion. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- PTM: The sulfation and the glycosylation are required for full
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the sulfated-peptide plant hormone family.
CC       {ECO:0000305}.
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DR   EMBL; AC004680; AAM14985.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC08333.1; -; Genomic_DNA.
DR   EMBL; AY085021; AAM61579.1; -; mRNA.
DR   EMBL; BT024520; ABD38859.1; -; mRNA.
DR   RefSeq; NP_565690.1; NM_128554.3.
DR   AlphaFoldDB; Q8S8P7; -.
DR   STRING; 3702.AT2G29995.1; -.
DR   PaxDb; Q8S8P7; -.
DR   PRIDE; Q8S8P7; -.
DR   EnsemblPlants; AT2G29995.1; AT2G29995.1; AT2G29995.
DR   GeneID; 817550; -.
DR   Gramene; AT2G29995.1; AT2G29995.1; AT2G29995.
DR   KEGG; ath:AT2G29995; -.
DR   Araport; AT2G29995; -.
DR   TAIR; locus:505006278; AT2G29995.
DR   eggNOG; ENOG502SEJX; Eukaryota.
DR   HOGENOM; CLU_197080_0_0_1; -.
DR   InParanoid; Q8S8P7; -.
DR   OMA; FKAKLCF; -.
DR   OrthoDB; 1634588at2759; -.
DR   PhylomeDB; Q8S8P7; -.
DR   PRO; PR:Q8S8P7; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q8S8P7; baseline and differential.
DR   Genevisible; Q8S8P7; AT.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR   InterPro; IPR034430; PSY.
DR   PANTHER; PTHR37177; PTHR37177; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Growth factor; Hydroxylation; Reference proteome; Secreted;
KW   Signal; Sulfation.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   PROPEP          26..49
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000365615"
FT   PEPTIDE         50..65
FT                   /note="Tyrosine-sulfated glycopeptide 3"
FT                   /id="PRO_0000365616"
FT   PROPEP          66..71
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000365617"
FT   REGION          47..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         51
FT                   /note="Sulfotyrosine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         63
FT                   /note="4-hydroxyproline"
FT                   /evidence="ECO:0000250"
FT   CARBOHYD        63
FT                   /note="O-linked (Ara...) hydroxyproline"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   71 AA;  7904 MW;  6CE9401BED53BFC9 CRC64;
     MGYSSSSRIG LCLFLFFTFA LLSSARISLS FSENEMTVVP ERSLMVSTND YSDPTANGRH
     DPPRGGRGRR R