PSYC_OIKKI
ID PSYC_OIKKI Reviewed; 45 AA.
AC P83421;
DT 15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 25-MAY-2022, entry version 55.
DE RecName: Full=Psychimicin;
OS Oiketicus kirbyi (Bagworm moth).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Tineoidea;
OC Psychidae; Oiketicinae; Oiketicus.
OX NCBI_TaxID=201386 {ECO:0000305};
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, FUNCTION, SUBUNIT, TISSUE SPECIFICITY, AND MASS
RP SPECTROMETRY.
RC TISSUE=Hemolymph;
RA Bulet P.;
RL Submitted (JUL-2002) to UniProtKB.
CC -!- FUNCTION: Has antimicrobial activity. Is particularly active against
CC fungi, and to a lesser extent against Gram-positive and Gram-negative
CC bacteria. {ECO:0000269|Ref.1, ECO:0000305}.
CC -!- SUBUNIT: Monomer. {ECO:0000269|Ref.1, ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Hemolymph. {ECO:0000269|Ref.1, ECO:0000305}.
CC -!- MASS SPECTROMETRY: Mass=5129.91; Method=MALDI;
CC Evidence={ECO:0000269|Ref.1};
CC -!- SIMILARITY: Belongs to the diapausin family. {ECO:0000305}.
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DR AlphaFoldDB; P83421; -.
DR SMR; P83421; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR Gene3D; 3.30.30.120; -; 1.
DR InterPro; IPR038203; Diapausin_sf.
PE 1: Evidence at protein level;
KW Antibiotic; Antimicrobial; Direct protein sequencing; Disulfide bond;
KW Fungicide; Immunity; Innate immunity; Secreted.
FT CHAIN 1..45
FT /note="Psychimicin"
FT /id="PRO_0000179985"
FT DISULFID 10..24
FT /evidence="ECO:0000250|UniProtKB:Q8T0W8"
FT DISULFID 14..36
FT /evidence="ECO:0000250|UniProtKB:Q8T0W8"
FT DISULFID 25..42
FT /evidence="ECO:0000250|UniProtKB:Q8T0W8"
SQ SEQUENCE 45 AA; 5135 MW; 4EF62CC412DA4BA9 CRC64;
INNWVRVPPC DQVCSRTNPE KDECCRAHGH AFHATCSGGM QCYRR