ID   PSYI_PSEAJ              Reviewed;         226 AA.
AC   P52990;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Acyl-homoserine-lactone synthase;
DE            EC=2.3.1.184;
DE   AltName: Full=Autoinducer synthesis protein PsyI;
GN   Name=psyI;
OS   Pseudomonas amygdali pv. tabaci (Pseudomonas syringae pv. tabaci).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas; Pseudomonas amygdali.
OX   NCBI_TaxID=322;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=PTBR2.024;
RA   Chen Y.C., Shaw P.D.;
RL   Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L-
CC       homoserine lactone), an autoinducer molecule.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-L-
CC         homoserine lactone + H(+) + holo-[ACP] + S-methyl-5'-thioadenosine;
CC         Xref=Rhea:RHEA:10096, Rhea:RHEA-COMP:9685, Rhea:RHEA-COMP:14125,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17509, ChEBI:CHEBI:55474,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:64479, ChEBI:CHEBI:138651;
CC         EC=2.3.1.184;
CC   -!- SIMILARITY: Belongs to the autoinducer synthase family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00533}.
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DR   EMBL; AF110468; AAA82063.1; -; Genomic_DNA.
DR   RefSeq; WP_005782177.1; NZ_QPDZ01000036.1.
DR   AlphaFoldDB; P52990; -.
DR   SMR; P52990; -.
DR   PRIDE; P52990; -.
DR   GeneID; 61869046; -.
DR   GO; GO:0061579; F:N-acyl homoserine lactone synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-KW.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR018311; Autoind_synth_CS.
DR   InterPro; IPR001690; Autoind_synthase.
DR   PANTHER; PTHR39322; PTHR39322; 1.
DR   Pfam; PF00765; Autoind_synth; 1.
DR   PRINTS; PR01549; AUTOINDCRSYN.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS00949; AUTOINDUCER_SYNTH_1; 1.
DR   PROSITE; PS51187; AUTOINDUCER_SYNTH_2; 1.
PE   3: Inferred from homology;
KW   Autoinducer synthesis; Quorum sensing; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..226
FT                   /note="Acyl-homoserine-lactone synthase"
FT                   /id="PRO_0000210892"
SQ   SEQUENCE   226 AA;  24946 MW;  1D996BE67A27E070 CRC64;
     MSSGFEFQLA SYTTMPVTLL ETLYSMRKKI FSDRLEWKVR VSHAFEFDEY DNAATTYLVG
     SWNGVPLAGL RLINTCDPYM LEGPFRSFFD CPAPKNAAMA ESSRFFVDTA RARSLGILHA
     PLTEMLLFSM HNHAALSGLQ SIITVVSKAM ARIVRKSGWE HHVLSTGEAS PGETVLLLEM
     PVTADNHQRL LGNIALRQPV TDDLLRWPIA LGVSGSAPQA CMHSAA