PT127_YEAST
ID PT127_YEAST Reviewed; 800 AA.
AC P32606; D6W283;
DT 01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 2.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Putative mitochondrial translation system component PET127;
GN Name=PET127; OrderedLocusNames=YOR017W; ORFNames=OR26.07;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 91-800.
RX PubMed=1279374; DOI=10.1007/bf00286182;
RA Haffter P.T., Fox T.D.;
RT "Suppression of carboxy-terminal truncations of the yeast mitochondrial
RT mRNA-specific translational activator PET122 by mutations in two new genes,
RT MRP17 and PET127.";
RL Mol. Gen. Genet. 235:64-73(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169874;
RA Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J.,
RA Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A.,
RA Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B.,
RA Dang V.-D., de Haan M., Delius H., Durand P., Fairhead C., Feldmann H.,
RA Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E.,
RA Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U.,
RA Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B.,
RA Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A.,
RA Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C.,
RA Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G.,
RA Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B.,
RA Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F.,
RA Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E.,
RA Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I.,
RA Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H.,
RA Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.";
RL Nature 387:98-102(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- FUNCTION: Could be a component of the mitochondrial translation system
CC with a role in promoting accuracy of translational initiation.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC -!- MISCELLANEOUS: Present with 1730 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: Belongs to the PET127 family. {ECO:0000305}.
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DR EMBL; X58363; CAA41257.1; -; Genomic_DNA.
DR EMBL; X87331; CAA60766.1; -; Genomic_DNA.
DR EMBL; Z74925; CAA99207.1; -; Genomic_DNA.
DR EMBL; BK006948; DAA10799.1; -; Genomic_DNA.
DR PIR; S54623; S54623.
DR RefSeq; NP_014660.1; NM_001183436.1.
DR AlphaFoldDB; P32606; -.
DR SMR; P32606; -.
DR BioGRID; 34421; 219.
DR DIP; DIP-895N; -.
DR IntAct; P32606; 7.
DR MINT; P32606; -.
DR STRING; 4932.YOR017W; -.
DR MaxQB; P32606; -.
DR PaxDb; P32606; -.
DR PRIDE; P32606; -.
DR EnsemblFungi; YOR017W_mRNA; YOR017W; YOR017W.
DR GeneID; 854182; -.
DR KEGG; sce:YOR017W; -.
DR SGD; S000005543; PET127.
DR VEuPathDB; FungiDB:YOR017W; -.
DR eggNOG; ENOG502QPU6; Eukaryota.
DR HOGENOM; CLU_003477_3_0_1; -.
DR InParanoid; P32606; -.
DR OMA; WEKCKIM; -.
DR BioCyc; YEAST:G3O-33565-MON; -.
DR PRO; PR:P32606; -.
DR Proteomes; UP000002311; Chromosome XV.
DR RNAct; P32606; protein.
DR GO; GO:0005740; C:mitochondrial envelope; IDA:SGD.
DR GO; GO:0005739; C:mitochondrion; HDA:SGD.
DR GO; GO:0000964; P:mitochondrial RNA 5'-end processing; IMP:SGD.
DR InterPro; IPR013943; Pet127.
DR PANTHER; PTHR31014; PTHR31014; 1.
DR Pfam; PF08634; Pet127; 1.
PE 1: Evidence at protein level;
KW Mitochondrion; Reference proteome.
FT CHAIN 1..800
FT /note="Putative mitochondrial translation system component
FT PET127"
FT /id="PRO_0000097082"
FT REGION 219..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 800 AA; 93408 MW; 8252F0FB1E7D4DE5 CRC64;
MGFYNCRFLS RRLSVEPCRI GSAAKSYQQR SIYHFGAALT NAPSGRETPD KLRSDLHSAL
EMVDEIYDTN STVEDIGNKE KGGRQKYTEE MDKAINLLKT NIKKEYRHDK YLERTKVGTY
PGRRTYPGRR TYPARRTYPA SRTYSDSNSY TFRINVQKIR HALVRYNQDG VQKHNQKPPR
IGHGLTRVLY QPLSLQKLRD NRSRMYNFDP AVENINPEYL EKKSEKDVNT DSSGEGQSKP
IFITPHKDES LLKVAKEHRK KYISSSSSMT SVLSQLHYLL SNFRRLNIID SSISKNFPQK
NCNYSESAYF PSAVILRKKR NGICSIDSDR SLDREIVLSV LGHYLEDFLT EKSLKNSSKS
ENYHYSSIDE FIVRSQLDAY DPNLPGTGVF DLKTRAVSAI RYDLSHVESN NNQTGYEIDK
VYGEFESLER EYFELIRSAL LKYSLQARIG KMDGIFVAYH NISKMFGFQY LPLDELDYII
HSSYNSKFDS LLKEKNDITK GIYGEEDYIL HYDRDDRKIA CLVANREFKM SMNLFSNILK
HVEQLLNSSN TKWEKCKIML KTEVEEKRSK SGRFFNEPVL NIVALPLSPE YEDKSLLVKD
TSNEQLTEEL LNLRSYNENL LEEHLNSLVG FKVNVKHFYH HHPNTTHLPD FALKKNDILD
TESRKYISDM MKRDWYKDIP STQTPNFFHA SDVSTWEVNS TFTDINDKQI LRKLYFKYLD
VKLNALKNQV ITRQEPDMSK KDEIMNRIKS LQARNDHRDN GSNKRYSNFG PTRLQTKLRA
YAKKGALRRK LLERSNKFHI
