ID   ATP22_KLULA             Reviewed;         711 AA.
AC   Q6CMA5;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Mitochondrial translation factor ATP22;
DE   Flags: Precursor;
GN   Name=ATP22; OrderedLocusNames=KLLA0E21813g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Translation factor specific for subunit 6 of the
CC       mitochondrial ATPase. Required for assembly of the CF(0) component of
CC       the ATPase (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATP22 family. {ECO:0000305}.
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DR   EMBL; CR382125; CAH00021.1; -; Genomic_DNA.
DR   RefSeq; XP_454934.1; XM_454934.1.
DR   AlphaFoldDB; Q6CMA5; -.
DR   STRING; 28985.XP_454934.1; -.
DR   PRIDE; Q6CMA5; -.
DR   EnsemblFungi; CAH00021; CAH00021; KLLA0_E21715g.
DR   GeneID; 2894614; -.
DR   KEGG; kla:KLLA0_E21715g; -.
DR   eggNOG; ENOG502QUX9; Eukaryota.
DR   HOGENOM; CLU_024415_0_0_1; -.
DR   InParanoid; Q6CMA5; -.
DR   OMA; INNCSEN; -.
DR   Proteomes; UP000000598; Chromosome E.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0045182; F:translation regulator activity; IEA:InterPro.
DR   InterPro; IPR017207; Atp22.
DR   PIRSF; PIRSF037437; Atp22; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transit peptide; Translation regulation.
FT   TRANSIT         1..28
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..711
FT                   /note="Mitochondrial translation factor ATP22"
FT                   /id="PRO_0000330047"
SQ   SEQUENCE   711 AA;  84724 MW;  6AB402094CD06FB8 CRC64;
     MFALSKSLRQ IKRQTIQYRF ISGISKDEVY CIIDTIKSSH EWHKLKQDQK MQAYVAEALT
     NPTSENVSEL MQLKRKMMRT LNENYNLALG YIEEGLPGPI ERLKFRSEFL RVVDSEHYAY
     FSKSLDHIRY CKGLDRATRR KEFYNCIELH RRCNPEVTEG SGILLPDDIH QWFFVFVPPD
     ERMKHYLFLI ENNVLISGHY AGLTQERMLK GSEMEYRVAS FLHFIEDPEK RHIFDEKFSV
     MHPFRPMRRI VNLLITKKDM VHIKEYLDVL TTRLENVELR NERIPYDVRK LYFIEFMHTL
     QHFARCTNYI DMFLETVHSM MDALPKDTPV PFIRKSFVEI LNYFQRIGDT ETVFKIMSMF
     NEYPLTEPNT KFTNEMLGRI LFSLRQFKDP KLTASYIVIA YKSIKTKKML NNLGLWCLIF
     GNGFGRLNKK AIRDAKQPEK FINLNVPESL RFKRAPDSVA LNELYIVVFD YYKSKLSPDE
     YRELVVKCYK YYCDFLKNHV NTYLQWRIDT SILRTMIHRA KFDIKDDRLA YEMLMNFYAM
     NLNPRFDSKN TPFGLVLYRN EAINQQEFNQ VLELMQRCRA PMDHKIIITI VLKFIKSGNI
     DLAHEWYTRL LKTGYPLRHF KMIEEAKRLN WDIPEPAERY YEECERKNQL EEENFDDIYL
     QNPAEDSYTN DLIEAAKKIG RIYATSIGAR IIPENDKAAM ELNQKKNAYG T