PT494_SACBA
ID PT494_SACBA Reviewed; 489 AA.
AC O59961;
DT 09-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 25-MAY-2022, entry version 47.
DE RecName: Full=COX3 mRNA-specific translational activator PET494;
GN Name=PET494;
OS Saccharomyces bayanus (Yeast) (Saccharomyces uvarum x Saccharomyces
OS eubayanus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=4931;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 76513 / CBS 380 / DSM 70412 / JCM 7258 / NBRC 1127 / NRRL
RC Y-12624;
RX PubMed=10757749; DOI=10.1093/genetics/154.3.999;
RA Costanzo M.C., Bonnefoy N., Williams E.H., Clark-Walker G.D., Fox T.D.;
RT "Highly diverged homologs of Saccharomyces cerevisiae mitochondrial mRNA-
RT specific translational activators have orthologous functions in other
RT budding yeasts.";
RL Genetics 154:999-1012(2000).
CC -!- FUNCTION: Required for the expression of the mitochondrial gene for
CC cytochrome c oxidase subunit III (COX3). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}.
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DR EMBL; AF056620; AAC13688.1; -; Genomic_DNA.
DR AlphaFoldDB; O59961; -.
DR SMR; O59961; -.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Activator; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW Translation regulation.
FT CHAIN 1..489
FT /note="COX3 mRNA-specific translational activator PET494"
FT /id="PRO_0000097084"
SQ SEQUENCE 489 AA; 57648 MW; 2C9776DB57536A4A CRC64;
MHLKKGKRSI GTVWRLLWKR LYSVHYKTNT YSTRSRKKLV TNFTRVNGLL LSCNGDTFPY
MRTLWRYFNA PGNLMFVTTN IITFTGIVAY NTMVTVSNER VFEEQMIAAQ MSLAKQKEEL
ETRALDFPAN HEQIKEADDA NCEQPAIERS GEDRSVKQQN EQLDSPIRHY SLTDLVLNKE
ARVADYDSQR VKASLFHMLY AYMLYRDTIQ PNSDSPNHNS EEWRHEVELL TRDKWLQGAH
QRIDVFYDLW NNQLDKIVTS PEKVQNFHLP NWSKYPTLLK FICTELHNNE LTTLDEFKQF
YGKVRSNEVK KLLGLWLYDH SFLFPRNIYD NKNQEVFYDT LISDSMQDNK IFQKYSSIVM
NPDNERTQLF FPNIYAQPVN KPIPSISLET YTRLLRGYIT LQETNCKYDY NDNIFKLISI
LKMNCFLQHD KKIRTGASVR ILLPRDEDRS PVLNTIPQAE KKTCYQILSK NRDILALLKR
ISDIQIDSS