PTA7_ARATH
ID PTA7_ARATH Reviewed; 161 AA.
AC Q8VZV9; F4KFT3; Q3YIT6; Q570R0;
DT 24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Protein PLASTID TRANSCRIPTIONALLY ACTIVE 7 {ECO:0000303|PubMed:16326926};
DE Short=pTAC7 {ECO:0000303|PubMed:16326926};
DE AltName: Full=Protein PIGMENT DEFECTIVE 225;
DE Flags: Precursor;
GN Name=PTAC7 {ECO:0000303|PubMed:16326926};
GN Synonyms=PDE225, TAC7 {ECO:0000303|PubMed:16326926};
GN OrderedLocusNames=At5g24314 {ECO:0000312|Araport:AT5G24314};
GN ORFNames=MOP9.14 {ECO:0000312|EMBL:AB006701};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:AAL36158.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT features of the regions of 1,044,062 bp covered by thirteen physically
RT assigned P1 clones.";
RL DNA Res. 4:291-300(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 15-50 (ISOFORM 1/2).
RC STRAIN=cv. Ag-0, cv. Gr-3, cv. Ita-0, cv. Kas-1, cv. Lip-0, cv. Me-0,
RC cv. Mt-0, cv. Oy-0, cv. Te-0, and cv. Tu-1;
RX PubMed=15911589; DOI=10.1534/genetics.104.036152;
RA Cork J.M., Purugganan M.D.;
RT "High-diversity genes in the Arabidopsis genome.";
RL Genetics 170:1897-1911(2005).
RN [6]
RP NOMENCLATURE.
RX PubMed=16326926; DOI=10.1105/tpc.105.036392;
RA Pfalz J., Liere K., Kandlbinder A., Dietz K.-J., Oelmueller R.;
RT "pTAC2, -6, and -12 are components of the transcriptionally active plastid
RT chromosome that are required for plastid gene expression.";
RL Plant Cell 18:176-197(2006).
RN [7]
RP FUNCTION, DISRUPTION PHENOTYPE, INTERACTION WITH FLN1; PTAC10; PTAC12 AND
RP PTAC14, SUBCELLULAR LOCATION, AND INDUCTION BY LIGHT.
RC STRAIN=cv. Columbia, and cv. Landsberg erecta;
RX PubMed=23082802; DOI=10.1111/j.1399-3054.2012.01718.x;
RA Yu Q.-B., Lu Y., Ma Q., Zhao T.-T., Huang C., Zhao H.-F., Zhang X.-L.,
RA Lv R.-H., Yang Z.-N.;
RT "TAC7, an essential component of the plastid transcriptionally active
RT chromosome complex, interacts with FLN1, TAC10, TAC12 and TAC14 to regulate
RT chloroplast gene expression in Arabidopsis thaliana.";
RL Physiol. Plantarum 148:408-421(2013).
CC -!- FUNCTION: Essential for chloroplast development, especially for
CC thylakoid formation. Involved in plastid gene expression, probably by
CC maintaining plastid-encoded RNA polymerase (PEP) activity.
CC {ECO:0000269|PubMed:23082802}.
CC -!- SUBUNIT: Component of the transcriptionally active chromosome (TAC)
CC complexes. Interacts with FLN1, PTAC10, PTAC12 and PTAC14.
CC {ECO:0000269|PubMed:23082802}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000269|PubMed:23082802}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8VZV9-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8VZV9-2; Sequence=VSP_057775;
CC -!- TISSUE SPECIFICITY: Mostly expressed in leaves, flowers and seedlings,
CC and, to a lower extent, in roots and stems.
CC {ECO:0000269|PubMed:23082802}.
CC -!- INDUCTION: By light. {ECO:0000269|PubMed:23082802}.
CC -!- DISRUPTION PHENOTYPE: Albino plants with defective chloroplasts
CC containing a few appressed membranes but lacking thylakoids, even when
CC grown under normal light conditions. Reduced plastid-encoded RNA
CC polymerase (PEP) activity. {ECO:0000269|PubMed:23082802}.
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DR EMBL; AB006701; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED93287.1; -; Genomic_DNA.
DR EMBL; CP002688; AED93288.1; -; Genomic_DNA.
DR EMBL; AY063802; AAL36158.1; -; mRNA.
DR EMBL; AY123012; AAM67545.1; -; mRNA.
DR EMBL; AK220647; BAD95132.1; -; mRNA.
DR EMBL; DQ132131; AAZ74736.1; -; Genomic_DNA.
DR EMBL; DQ132132; AAZ74737.1; -; Genomic_DNA.
DR EMBL; DQ132133; AAZ74738.1; -; Genomic_DNA.
DR EMBL; DQ132134; AAZ74739.1; -; Genomic_DNA.
DR EMBL; DQ132135; AAZ74740.1; -; Genomic_DNA.
DR EMBL; DQ132136; AAZ74741.1; -; Genomic_DNA.
DR EMBL; DQ132137; AAZ74742.1; -; Genomic_DNA.
DR EMBL; DQ132142; AAZ74747.1; -; Genomic_DNA.
DR EMBL; DQ132143; AAZ74748.1; -; Genomic_DNA.
DR EMBL; DQ132144; AAZ74749.1; -; Genomic_DNA.
DR RefSeq; NP_001190379.1; NM_001203450.1. [Q8VZV9-2]
DR RefSeq; NP_680215.1; NM_147910.4. [Q8VZV9-1]
DR AlphaFoldDB; Q8VZV9; -.
DR IntAct; Q8VZV9; 2.
DR STRING; 3702.AT5G24314.2; -.
DR PaxDb; Q8VZV9; -.
DR PRIDE; Q8VZV9; -.
DR ProteomicsDB; 248843; -. [Q8VZV9-1]
DR EnsemblPlants; AT5G24314.1; AT5G24314.1; AT5G24314. [Q8VZV9-1]
DR EnsemblPlants; AT5G24314.2; AT5G24314.2; AT5G24314. [Q8VZV9-2]
DR GeneID; 832500; -.
DR Gramene; AT5G24314.1; AT5G24314.1; AT5G24314. [Q8VZV9-1]
DR Gramene; AT5G24314.2; AT5G24314.2; AT5G24314. [Q8VZV9-2]
DR KEGG; ath:AT5G24314; -.
DR Araport; AT5G24314; -.
DR TAIR; locus:504954893; AT5G24314.
DR eggNOG; ENOG502RZZ1; Eukaryota.
DR OMA; RDIWETG; -.
DR OrthoDB; 1400547at2759; -.
DR PRO; PR:Q8VZV9; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q8VZV9; baseline and differential.
DR GO; GO:0009507; C:chloroplast; IDA:UniProtKB.
DR GO; GO:0042644; C:chloroplast nucleoid; HDA:TAIR.
DR GO; GO:0000427; C:plastid-encoded plastid RNA polymerase complex; IDA:UniProtKB.
DR GO; GO:0009658; P:chloroplast organization; IMP:UniProtKB.
DR GO; GO:0042793; P:plastid transcription; IMP:UniProtKB.
DR GO; GO:0009416; P:response to light stimulus; IEP:UniProtKB.
DR GO; GO:0010027; P:thylakoid membrane organization; IMP:UniProtKB.
DR InterPro; IPR038958; PTAC7.
DR PANTHER; PTHR37257; PTHR37257; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Chloroplast; Plastid; Reference proteome;
KW Transcription; Transcription regulation; Transit peptide.
FT TRANSIT 1..32
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 33..161
FT /note="Protein PLASTID TRANSCRIPTIONALLY ACTIVE 7"
FT /evidence="ECO:0000255"
FT /id="PRO_0000433433"
FT VAR_SEQ 49
FT /note="T -> TLVSTKLDI (in isoform 2)"
FT /id="VSP_057775"
FT CONFLICT 16
FT /note="I -> V (in Ref. 4; BAD95132)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 161 AA; 18732 MW; F5E40AD38F36993B CRC64;
MASFTCSSPS SILPIIDTRS GNLRCTFQSQ VSCGIQRDDN GRRVWRRRTL TKKDDMLRYK
MQRVPFVEEQ VRKIREVGKV MTMDIEQLLL REDNRFEFVN SVAAEATEYV DKNRDEYGGS
KKAIFHVLSN RVNDLGFDRP EAYVEADPYK PGPGYLLEYY T
