PTAR1_DANRE
ID PTAR1_DANRE Reviewed; 426 AA.
AC A3KPW7; Q08CA2;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 03-APR-2007, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Protein prenyltransferase alpha subunit repeat-containing protein 1;
GN Name=ptar1; ORFNames=si:ch211-117c19.3;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein prenyltransferase subunit alpha
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAI24322.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; BX470086; CAM56295.1; -; Genomic_DNA.
DR EMBL; BC124321; AAI24322.1; ALT_INIT; mRNA.
DR RefSeq; NP_001123546.1; NM_001130074.1.
DR AlphaFoldDB; A3KPW7; -.
DR SMR; A3KPW7; -.
DR STRING; 7955.ENSDARP00000050982; -.
DR PaxDb; A3KPW7; -.
DR PeptideAtlas; A3KPW7; -.
DR Ensembl; ENSDART00000162022; ENSDARP00000133028; ENSDARG00000102338.
DR GeneID; 561820; -.
DR KEGG; dre:561820; -.
DR CTD; 375743; -.
DR ZFIN; ZDB-GENE-060526-17; ptar1.
DR eggNOG; ENOG502QQUP; Eukaryota.
DR GeneTree; ENSGT00390000017892; -.
DR HOGENOM; CLU_048186_2_0_1; -.
DR InParanoid; A3KPW7; -.
DR OMA; CCNTEQR; -.
DR OrthoDB; 1527547at2759; -.
DR PhylomeDB; A3KPW7; -.
DR TreeFam; TF324310; -.
DR PRO; PR:A3KPW7; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 5.
DR Bgee; ENSDARG00000102338; Expressed in mature ovarian follicle and 21 other tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0008318; F:protein prenyltransferase activity; IEA:InterPro.
DR GO; GO:0018342; P:protein prenylation; IBA:GO_Central.
DR InterPro; IPR002088; Prenyl_trans_a.
DR Pfam; PF01239; PPTA; 4.
DR PROSITE; PS51147; PFTA; 5.
PE 2: Evidence at transcript level;
KW Prenyltransferase; Reference proteome; Repeat; Transferase.
FT CHAIN 1..426
FT /note="Protein prenyltransferase alpha subunit repeat-
FT containing protein 1"
FT /id="PRO_0000316844"
FT REPEAT 86..119
FT /note="PFTA 1"
FT REPEAT 121..154
FT /note="PFTA 2"
FT REPEAT 180..213
FT /note="PFTA 3"
FT REPEAT 219..252
FT /note="PFTA 4"
FT REPEAT 290..323
FT /note="PFTA 5"
FT REGION 255..279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..273
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 92
FT /note="S -> C (in Ref. 2; AAI24322)"
FT /evidence="ECO:0000305"
FT CONFLICT 270
FT /note="N -> S (in Ref. 2; AAI24322)"
FT /evidence="ECO:0000305"
FT CONFLICT 354
FT /note="I -> T (in Ref. 2; AAI24322)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 426 AA; 49327 MW; 59339165EF0CB5CA CRC64;
MAESEEEVDV LVQRVVKDIT NAFKRNPNID EIGLIPCPEA RYNRSPIVLV ENKLGVESWC
VKFLLPYVHN KLLLYRQRKQ WLDREALVDI TSTLLLLNPD FTTAWNVRKE LLQCGVLNPE
KDLYLGKLAL SKHPKSPETW IHRRWVLQRL QKECSPSGQE LKDSAESRRQ CERLQRALQE
EMRVCAEAAG RYPSNYNAWS HRIWVLQNMA KGNLKVLHDE LSSTRLWVSM HVSDHSGFHY
RQHLLKALAK ELSPAAEKDV HTSQQPNGEN TATASDDNHH KDVMPRLFHE EIQLCTDLIE
SYPGHETLWC HRRHVFYLWH QWRREHMQGA GSQSPALTHT DVLLSKELCD NNSISQAMDI
DCVLDGSKHG SYTQDTKRLK RGPLLLQPGF PSEHTFISRI LTGCRNPEQS RFAIAYRKWL
DSVIGQ
