ID   PTAR1_PESFW             Reviewed;         418 AA.
AC   A0A067XNJ0; W3WSV9;
DT   31-JAN-2018, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2014, sequence version 1.
DT   25-MAY-2022, entry version 16.
DE   RecName: Full=Pestheic acid cluster transcriptional regulator 1 {ECO:0000303|PubMed:24302702};
GN   Name=ptaR1 {ECO:0000303|PubMed:24302702}; ORFNames=PFICI_10832;
OS   Pestalotiopsis fici (strain W106-1 / CGMCC3.15140).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Sporocadaceae; Pestalotiopsis.
OX   NCBI_TaxID=1229662;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=W106-1 / CGMCC3.15140;
RX   PubMed=24302702; DOI=10.1002/cbic.201300626;
RA   Xu X., Liu L., Zhang F., Wang W., Li J., Guo L., Che Y., Liu G.;
RT   "Identification of the first diphenyl ether gene cluster for pestheic acid
RT   biosynthesis in plant endophyte Pestalotiopsis fici.";
RL   ChemBioChem 15:284-292(2014).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W106-1 / CGMCC3.15140;
RX   PubMed=25623211; DOI=10.1186/s12864-014-1190-9;
RA   Wang X., Zhang X., Liu L., Xiang M., Wang W., Sun X., Che Y., Guo L.,
RA   Liu G., Guo L., Wang C., Yin W.B., Stadler M., Zhang X., Liu X.;
RT   "Genomic and transcriptomic analysis of the endophytic fungus
RT   Pestalotiopsis fici reveals its lifestyle and high potential for synthesis
RT   of natural products.";
RL   BMC Genomics 16:28-28(2015).
CC   -!- FUNCTION: Transcription factor that, with ptaR2 and ptaR3, coregulates
CC       the expression of the gene cluster that mediates the biosynthesis of
CC       pestheic acid, a diphenyl ether which is a biosynthetic precursor of
CC       the unique chloropupukeananes (PubMed:24302702).
CC       {ECO:0000305|PubMed:24302702}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR   EMBL; KC145148; AGO59050.1; -; Genomic_DNA.
DR   EMBL; KI912116; ETS76958.1; -; Genomic_DNA.
DR   RefSeq; XP_007837604.1; XM_007839413.1.
DR   AlphaFoldDB; A0A067XNJ0; -.
DR   SMR; A0A067XNJ0; -.
DR   EnsemblFungi; ETS76958; ETS76958; PFICI_10832.
DR   GeneID; 19275845; -.
DR   KEGG; pfy:PFICI_10832; -.
DR   eggNOG; KOG3178; Eukaryota.
DR   OMA; LLACIQW; -.
DR   OrthoDB; 817726at2759; -.
DR   Proteomes; UP000030651; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   4: Predicted;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..418
FT                   /note="Pestheic acid cluster transcriptional regulator 1"
FT                   /id="PRO_0000443052"
FT   REGION          244..272
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        244..263
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   418 AA;  45632 MW;  42B6CAF2E1CE9DD1 CRC64;
     MSSVPIDSVQ AAQQVVSTKI KDKSWIMPTD PAEFLQQIAY QSQLLACLHW LGEFQILACV
     PLSGSVPIKD VADLAGVPVS QLAHVIRFMA TAGFMKEPRR GEVAHTPQSA AFVTDPSFLD
     AGIFLAQVSA RSARKMAQNS AISTLMGGDG ANNGSDFDNG ELLKSTSESP RVQREVTAYL
     HYVVNEVSDT ANLLAQLDWR KLGSSSVVEI RADRIYPASL VLTELHSTPR FTVQTFQEDS
     VEQGTAVTTT ATTSSSFISK SSEEPSPKRI KPGITYQKRS LGSPQVVTDA TMYVMRLERP
     HSTSVQRSIL DEGQIVSELR AHLGVLKHNS NATLILIGPL LPEAGAIDAK AEMVVRFRDL
     SLNQLTSERE MEVGELVDII GDVQDESGCL VVVNKLYSRT SSTVALEVRY ELYNYRKG