PTAS_MYCPN
ID PTAS_MYCPN Reviewed; 320 AA.
AC P75359;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Phosphate acetyltransferase;
DE EC=2.3.1.8;
DE AltName: Full=Phosphotransacetylase;
GN Name=pta; OrderedLocusNames=MPN_428; ORFNames=MP413;
OS Mycoplasma pneumoniae (strain ATCC 29342 / M129) (Mycoplasmoides
OS pneumoniae).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=272634;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29342 / M129;
RX PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.;
RT "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT pneumoniae.";
RL Nucleic Acids Res. 24:4420-4449(1996).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + phosphate = acetyl phosphate + CoA;
CC Xref=Rhea:RHEA:19521, ChEBI:CHEBI:22191, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=2.3.1.8;
CC -!- PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis;
CC acetyl-CoA from acetate: step 2/2.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the phosphate acetyltransferase and
CC butyryltransferase family. {ECO:0000305}.
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DR EMBL; U00089; AAB96061.1; -; Genomic_DNA.
DR PIR; S73739; S73739.
DR RefSeq; NP_110116.1; NC_000912.1.
DR RefSeq; WP_010874784.1; NC_000912.1.
DR AlphaFoldDB; P75359; -.
DR SMR; P75359; -.
DR IntAct; P75359; 2.
DR STRING; 272634.MPN_428; -.
DR EnsemblBacteria; AAB96061; AAB96061; MPN_428.
DR KEGG; mpn:MPN_428; -.
DR PATRIC; fig|272634.6.peg.463; -.
DR HOGENOM; CLU_019723_0_1_14; -.
DR OMA; TMLVKMG; -.
DR BioCyc; MetaCyc:MON-602; -.
DR BioCyc; MPNE272634:G1GJ3-692-MON; -.
DR UniPathway; UPA00340; UER00459.
DR Proteomes; UP000000808; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008959; F:phosphate acetyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006085; P:acetyl-CoA biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10750; -; 1.
DR Gene3D; 3.40.50.10950; -; 1.
DR InterPro; IPR012147; P_Ac_Bu_trans.
DR InterPro; IPR004614; P_AcTrfase.
DR InterPro; IPR042113; P_AcTrfase_dom1.
DR InterPro; IPR042112; P_AcTrfase_dom2.
DR InterPro; IPR002505; PTA_PTB.
DR Pfam; PF01515; PTA_PTB; 1.
DR PIRSF; PIRSF000428; P_Ac_trans; 1.
DR TIGRFAMs; TIGR00651; pta; 1.
PE 3: Inferred from homology;
KW Acyltransferase; Cytoplasm; Reference proteome; Transferase.
FT CHAIN 1..320
FT /note="Phosphate acetyltransferase"
FT /id="PRO_0000179134"
SQ SEQUENCE 320 AA; 35219 MW; DD1E674A6E4E898F CRC64;
MSVIDLLKQR VQSAGKKPVI IFPEGWSPTV MEAVNQLQQA GILTPPVIFR TRSEVPAGFN
TAIKHYVIEE MDLTKYANFV YEKRKHKGME MREAQKFVRD ASSLAATLVA LNEVDGEVCG
KEYATKDTLR PALQLLGTGN FVSSVFIMEK NEERLYFTDC AFAVYPSPQE LAVVAENTFK
FAQSMGEPEL KMVFLSYSTL GSGKGEAVDK VVSATQIFLE KHPELKANVC GELQFDSAFV
EKVRKQKAPN LTWNGSANIY VFPNLDAGNI GYKIAQRLGG YEAIGPIVLG LARPFNDLSR
GASVSDVFNV GIITAAQTLK