PTAS_RICPR
ID PTAS_RICPR Reviewed; 351 AA.
AC Q9ZE39;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 92.
DE RecName: Full=Phosphate acetyltransferase;
DE EC=2.3.1.8;
DE AltName: Full=Phosphotransacetylase;
GN Name=pta; OrderedLocusNames=RP109;
OS Rickettsia prowazekii (strain Madrid E).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX NCBI_TaxID=272947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Madrid E;
RX PubMed=9823893; DOI=10.1038/24094;
RA Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T.,
RA Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H.,
RA Kurland C.G.;
RT "The genome sequence of Rickettsia prowazekii and the origin of
RT mitochondria.";
RL Nature 396:133-140(1998).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + phosphate = acetyl phosphate + CoA;
CC Xref=Rhea:RHEA:19521, ChEBI:CHEBI:22191, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=2.3.1.8;
CC -!- PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis;
CC acetyl-CoA from acetate: step 2/2.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the phosphate acetyltransferase and
CC butyryltransferase family. {ECO:0000305}.
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DR EMBL; AJ235270; CAA14578.1; -; Genomic_DNA.
DR PIR; C71720; C71720.
DR RefSeq; NP_220501.1; NC_000963.1.
DR RefSeq; WP_004597142.1; NC_000963.1.
DR AlphaFoldDB; Q9ZE39; -.
DR SMR; Q9ZE39; -.
DR STRING; 272947.RP109; -.
DR EnsemblBacteria; CAA14578; CAA14578; CAA14578.
DR GeneID; 57569237; -.
DR KEGG; rpr:RP109; -.
DR PATRIC; fig|272947.5.peg.111; -.
DR eggNOG; COG0280; Bacteria.
DR HOGENOM; CLU_056531_1_0_5; -.
DR OMA; CIVDGPF; -.
DR UniPathway; UPA00340; UER00459.
DR Proteomes; UP000002480; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008959; F:phosphate acetyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006085; P:acetyl-CoA biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR012147; P_Ac_Bu_trans.
DR InterPro; IPR002505; PTA_PTB.
DR Pfam; PF01515; PTA_PTB; 1.
DR PIRSF; PIRSF000428; P_Ac_trans; 1.
PE 3: Inferred from homology;
KW Acyltransferase; Cytoplasm; Reference proteome; Transferase.
FT CHAIN 1..351
FT /note="Phosphate acetyltransferase"
FT /id="PRO_0000179138"
SQ SEQUENCE 351 AA; 38170 MW; 2713B57086B49369 CRC64;
MKKQHIINET FLDEILAQKL GTTYIPPTEI KDSDFDKAAK HFINLLLRAD GLKPIKTAVV
HPIDKESLLG AVRAAQFNVI KPILIGPQHK IESVAKVNDV DLENYQVINA EHSHEAAKKA
VELAKKREVA AIMKGALHTD ELMSAVVYKE NGLRTERRIS HAFLMAVATF PKPFIITDAA
INIRPTLEDK RDIVQNAIDL MHIIKEDKQV RVAVLSAVET VTSAIPTTLD AAALSKMADR
GQITNAVVDG PLAFDNAISL FAAEAKGISS PVSGNADILV VPDLESGNML AKQLKYLGQA
VMAGIVLGAR VPIILTSRAD PIDMRVISCV LASFIYNQTK AKLHNSSKSI I