ID   PTB_CLOAB               Reviewed;         301 AA.
AC   P58255;
DT   29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   29-AUG-2001, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Phosphate butyryltransferase;
DE            EC=2.3.1.19;
DE   AltName: Full=Phosphotransbutyrylase;
GN   Name=ptb; OrderedLocusNames=CA_C3076;
OS   Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS   / VKM B-1787).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=272562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
RX   PubMed=11466286; DOI=10.1128/jb.183.16.4823-4838.2001;
RA   Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA   Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA   Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA   Smith D.R.;
RT   "Genome sequence and comparative analysis of the solvent-producing
RT   bacterium Clostridium acetobutylicum.";
RL   J. Bacteriol. 183:4823-4838(2001).
CC   -!- FUNCTION: Catalyzes the conversion of butyryl-CoA through butyryl
CC       phosphate to butyrate. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=butanoyl-CoA + phosphate = butanoyl phosphate + CoA;
CC         Xref=Rhea:RHEA:20892, ChEBI:CHEBI:43474, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57371, ChEBI:CHEBI:58079; EC=2.3.1.19;
CC   -!- PATHWAY: Lipid metabolism; butanoate metabolism.
CC   -!- SIMILARITY: Belongs to the phosphate acetyltransferase and
CC       butyryltransferase family. {ECO:0000305}.
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DR   EMBL; AE001437; AAK81016.1; -; Genomic_DNA.
DR   PIR; E97278; E97278.
DR   RefSeq; NP_349676.1; NC_003030.1.
DR   RefSeq; WP_010966357.1; NC_003030.1.
DR   AlphaFoldDB; P58255; -.
DR   SMR; P58255; -.
DR   STRING; 272562.CA_C3076; -.
DR   EnsemblBacteria; AAK81016; AAK81016; CA_C3076.
DR   GeneID; 44999563; -.
DR   KEGG; cac:CA_C3076; -.
DR   PATRIC; fig|272562.8.peg.3259; -.
DR   eggNOG; COG0280; Bacteria.
DR   HOGENOM; CLU_056531_0_0_9; -.
DR   OMA; CIVDGPF; -.
DR   OrthoDB; 1301815at2; -.
DR   BioCyc; MetaCyc:PTBCLOS-MON; -.
DR   BRENDA; 2.3.1.19; 1452.
DR   SABIO-RK; P58255; -.
DR   UniPathway; UPA00863; -.
DR   Proteomes; UP000000814; Chromosome.
DR   GO; GO:0050182; F:phosphate butyryltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019605; P:butyrate metabolic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR012147; P_Ac_Bu_trans.
DR   InterPro; IPR014079; Phosphate_butyryltransferase.
DR   InterPro; IPR002505; PTA_PTB.
DR   Pfam; PF01515; PTA_PTB; 1.
DR   PIRSF; PIRSF000428; P_Ac_trans; 1.
DR   TIGRFAMs; TIGR02706; P_butyryltrans; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..301
FT                   /note="Phosphate butyryltransferase"
FT                   /id="PRO_0000179152"
SQ   SEQUENCE   301 AA;  32228 MW;  B92A01C4E5EA7F73 CRC64;
     MIKSFNEIIM KVKSKEMKKV AVAVAQDEPV LEAVRDAKKN GIADAILVGD HDEIVSIALK
     IGMDVNDFEI VNEPNVKKAA LKAVELVSTG KADMVMKGLV NTATFLRSVL NKEVGLRTGK
     TMSHVAVFET EKFDRLLFLT DVAFNTYPEL KEKIDIVNNS VKVAHAIGIE NPKVAPICAV
     EVINPKMPST LDAAMLSKMS DRGQIKGCVV DGPLALDIAL SEEAAHHKGV TGEVAGKADI
     FLMPNIETGN VMYKTLTYTT DSKNGGILVG TSAPVVLTSR ADSHETKMNS IALAALVAGN
     K