ID   PTCD2_BOVIN             Reviewed;         384 AA.
AC   Q3SZ55;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Pentatricopeptide repeat-containing protein 2, mitochondrial;
GN   Name=PTCD2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in mitochondrial RNA maturation and mitochondrial
CC       respiratory chain function. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PTCD2 family. {ECO:0000305}.
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DR   EMBL; BC103129; AAI03130.1; -; mRNA.
DR   RefSeq; NP_001030375.1; NM_001035298.2.
DR   AlphaFoldDB; Q3SZ55; -.
DR   SMR; Q3SZ55; -.
DR   STRING; 9913.ENSBTAP00000019535; -.
DR   PaxDb; Q3SZ55; -.
DR   PRIDE; Q3SZ55; -.
DR   Ensembl; ENSBTAT00000019535; ENSBTAP00000019535; ENSBTAG00000014675.
DR   GeneID; 514705; -.
DR   KEGG; bta:514705; -.
DR   CTD; 79810; -.
DR   VEuPathDB; HostDB:ENSBTAG00000014675; -.
DR   VGNC; VGNC:33490; PTCD2.
DR   eggNOG; ENOG502R1K6; Eukaryota.
DR   GeneTree; ENSGT00390000009329; -.
DR   HOGENOM; CLU_060975_0_0_1; -.
DR   InParanoid; Q3SZ55; -.
DR   OMA; IYRYHEQ; -.
DR   OrthoDB; 497711at2759; -.
DR   TreeFam; TF324851; -.
DR   Proteomes; UP000009136; Chromosome 20.
DR   Bgee; ENSBTAG00000014675; Expressed in rectus femoris and 104 other tissues.
DR   GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0007005; P:mitochondrion organization; IBA:GO_Central.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0055001; P:muscle cell development; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0050684; P:regulation of mRNA processing; ISS:UniProtKB.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IEA:Ensembl.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR034913; MRPS27/PTCD2.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR034629; PTCD2.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR14700; PTHR14700; 1.
DR   Pfam; PF10037; MRP-S27; 1.
DR   TIGRFAMs; TIGR00756; PPR; 1.
DR   PROSITE; PS51375; PPR; 1.
PE   2: Evidence at transcript level;
KW   Mitochondrion; mRNA processing; Phosphoprotein; Reference proteome.
FT   CHAIN           1..384
FT                   /note="Pentatricopeptide repeat-containing protein 2,
FT                   mitochondrial"
FT                   /id="PRO_0000344049"
FT   REPEAT          162..196
FT                   /note="PPR"
FT   MOD_RES         378
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8WV60"
SQ   SEQUENCE   384 AA;  43945 MW;  E1771C6F35BF9F6F CRC64;
     MAATLRPPKQ VLLLHALRSL VYHWVGGSGS TCCLCPLGAK RYLLTDSIVK LKEFQRKKVA
     VACNLPGTKE TYLRNLEEKL TQNKLILKEE LRTLLHLCTS RDDVELAKHV IYRYHAENRN
     ITLGEYKFGP LFVRLCYELD LEDSAVELIK DQHLQGFFSD STSFNILMDM LFIKGKYRSA
     LEVLIQMKNQ DLKFNKDTYV LAFAICYKLN SPESFQICTT LREEALIKGE ILPRRASCFA
     VALALNQNQV AKAISIFSQI MNPESIICTN LNIMIHIQSN MLKTLIDILK DATEGNLSRF
     VKRHVFSEEV LVKVREKVKD VPALLAEFDE LNKKLHRSGQ VTAYTLDALL CHTPSDRQSY
     TVLLNKRTVS RRTFQPLSQS LWAE