PTCD2_PONAB
ID PTCD2_PONAB Reviewed; 383 AA.
AC Q5R503;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 25-MAY-2022, entry version 49.
DE RecName: Full=Pentatricopeptide repeat-containing protein 2, mitochondrial;
GN Name=PTCD2;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain cortex;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in mitochondrial RNA maturation and mitochondrial
CC respiratory chain function. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PTCD2 family. {ECO:0000305}.
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DR EMBL; CR861082; CAH93163.1; -; mRNA.
DR RefSeq; NP_001126866.1; NM_001133394.1.
DR AlphaFoldDB; Q5R503; -.
DR GeneID; 100173875; -.
DR KEGG; pon:100173875; -.
DR CTD; 79810; -.
DR InParanoid; Q5R503; -.
DR OrthoDB; 497711at2759; -.
DR Proteomes; UP000001595; Unplaced.
DR GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0050684; P:regulation of mRNA processing; ISS:UniProtKB.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR034913; MRPS27/PTCD2.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR034629; PTCD2.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR14700; PTHR14700; 1.
DR Pfam; PF10037; MRP-S27; 1.
DR TIGRFAMs; TIGR00756; PPR; 1.
DR PROSITE; PS51375; PPR; 1.
PE 2: Evidence at transcript level;
KW Mitochondrion; mRNA processing; Phosphoprotein; Reference proteome.
FT CHAIN 1..383
FT /note="Pentatricopeptide repeat-containing protein 2,
FT mitochondrial"
FT /id="PRO_0000344052"
FT REPEAT 161..195
FT /note="PPR"
FT MOD_RES 377
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8WV60"
SQ SEQUENCE 383 AA; 43199 MW; 4B89259BBF268E93 CRC64;
MAAALRPSNR VLLQALQTLV YPGVGGSGSV SCRCPVGAKR YLLTDNVVKL KEFQQKKVAI
ACNLSGTKEM YFRNLKEKLT QNKLILKGEL ITLLHLCESR DHVELAKNVI YRYHAENKNF
TLGEYKFGPL FMRLCYELNL EESAVELVKD QHLRGFFSDS TSFNILMDML FIKGKYKSAL
EVLIEMKNQN VKFTTDTYVL AFAICYKLNS PESFKICTIL GEKALLKGEI LSRRASCFAV
ALALNQNEVA KAMSIFSQIM NPESIACVNL NIIIHIQSNM LENLIKTLNN AAEGNLSKFV
KRNVFSEEVL AKVREKVKDV PALVAKFDEI YGILHITGQV TTDSLDAVLC HTPKDRKSHM
LLLNKRMFSR RTSQPLSQSL LAE