ID   PTCD3_XENLA             Reviewed;         669 AA.
AC   Q32N55; Q52KZ1;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Pentatricopeptide repeat domain-containing protein 3, mitochondrial;
DE   Flags: Precursor;
GN   Name=ptcd3;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo, and Eye;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mitochondrial protein that may have a role in mitochondrial
CC       translation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC       mS39 family. {ECO:0000305}.
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DR   EMBL; BC094135; AAH94135.1; -; mRNA.
DR   EMBL; BC108830; AAI08831.1; -; mRNA.
DR   RefSeq; NP_001089914.1; NM_001096445.1.
DR   AlphaFoldDB; Q32N55; -.
DR   SMR; Q32N55; -.
DR   DNASU; 734981; -.
DR   GeneID; 734981; -.
DR   KEGG; xla:734981; -.
DR   CTD; 734981; -.
DR   Xenbase; XB-GENE-961486; ptcd3.L.
DR   OrthoDB; 405419at2759; -.
DR   Proteomes; UP000186698; Chromosome 1L.
DR   Bgee; 734981; Expressed in heart and 19 other tissues.
DR   GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0043024; F:ribosomal small subunit binding; ISS:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; ISS:UniProtKB.
DR   GO; GO:0032543; P:mitochondrial translation; ISS:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 2.
DR   InterPro; IPR002885; Pentatricopeptide_repeat.
DR   InterPro; IPR037387; PTCD3.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR16276; PTHR16276; 1.
DR   Pfam; PF13812; PPR_3; 1.
DR   PROSITE; PS51375; PPR; 4.
PE   2: Evidence at transcript level;
KW   Mitochondrion; Reference proteome; Repeat; Ribonucleoprotein;
KW   Ribosomal protein; RNA-binding; rRNA-binding; Transit peptide;
KW   Translation regulation.
FT   TRANSIT         1..13
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           14..669
FT                   /note="Pentatricopeptide repeat domain-containing protein
FT                   3, mitochondrial"
FT                   /id="PRO_0000305032"
FT   REPEAT          129..163
FT                   /note="PPR 1"
FT   REPEAT          164..199
FT                   /note="PPR 2"
FT   REPEAT          209..239
FT                   /note="PPR 3"
FT   REPEAT          240..274
FT                   /note="PPR 4"
FT   REPEAT          275..314
FT                   /note="PPR 5"
FT   REPEAT          315..351
FT                   /note="PPR 6"
FT   REPEAT          352..392
FT                   /note="PPR 7"
FT   REPEAT          396..430
FT                   /note="PPR 8"
FT   REPEAT          438..472
FT                   /note="PPR 9"
FT   REPEAT          473..507
FT                   /note="PPR 10"
FT   REPEAT          556..590
FT                   /note="PPR 11"
FT   REGION          186..218
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          648..669
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        200..214
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        489
FT                   /note="C -> R (in Ref. 1; AAH94135)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        638
FT                   /note="N -> S (in Ref. 1; AAH94135)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   669 AA;  76252 MW;  A5EE65695AD8F135 CRC64;
     MAAPCVRLGS VRCTGTLLRY FCGSARHQAA AASHEEIDIP RRKSWDKTAV LQALAYTVSH
     DPTAAHYMFQ DDPFLVPKTS SEFRLYSLSK ESGRNAAKYI IGTHPKLFQN DIAEPHIPCL
     MPENFQPQIE GVSEEALKER IQLRRIKESI DLFDQLLQGG TAPSLETTNR LLDLICFYGD
     REPTRDIQTS EQNQQDDQDQ QETEDSKKRP GQYRKASEIL GSWRENNNAE RIFNLMPERN
     AHSFCTLIQG MVKYGSSNKA FNTYTDLMNN RLTADVQTFN ALILAAPDMK EKYNEKWDLI
     VELLKHMVQQ NVRPNLLTFN SVLKSLRKCG TMARGLALQT INEMKALNIE PSLGTYNHLL
     GVFYKGALSP RGQTEILSEV LDEIEGRSFT LRDPDDVYFF TNAMRVCLDL KDIELAYRLH
     ALQQTADNRG LMGDFYLQST YYGRFFNLLC MMENIDVILK WYRELIPSLY YPNSRGMLDL
     LQALDMDNCL DLIPQIWKDI KQIGHSNKVE LVEEVLKLMA RDVQPAELQA AFADTALDIK
     SLYEVRDRVR IVLEWSSASL GNISVLLARA GRTEEAWKML QRFKTNHRVP STEVVDEFLS
     RAKMDANTNL AISLVQLAVG FSLPNTGKLA ERVMEEFNVS EEQRLTLEDL QKSHSSSSSS
     SESSDSDRE