ID   ATP23_DANRE             Reviewed;         254 AA.
AC   A4IGF3;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Mitochondrial inner membrane protease ATP23 homolog;
DE            EC=3.4.24.-;
GN   Name=atp23; Synonyms=xrcc6bp1; ORFNames=zgc:162885;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M76 family. {ECO:0000305}.
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DR   EMBL; BC135073; AAI35074.1; -; mRNA.
DR   RefSeq; NP_001077049.1; NM_001083580.1.
DR   AlphaFoldDB; A4IGF3; -.
DR   STRING; 7955.ENSDARP00000087721; -.
DR   MEROPS; M76.001; -.
DR   PaxDb; A4IGF3; -.
DR   PeptideAtlas; A4IGF3; -.
DR   Ensembl; ENSDART00000093289; ENSDARP00000087721; ENSDARG00000063686.
DR   GeneID; 100004177; -.
DR   KEGG; dre:100004177; -.
DR   CTD; 91419; -.
DR   ZFIN; ZDB-GENE-070410-102; atp23.
DR   eggNOG; KOG3314; Eukaryota.
DR   GeneTree; ENSGT00390000010948; -.
DR   HOGENOM; CLU_079125_1_0_1; -.
DR   InParanoid; A4IGF3; -.
DR   OMA; VDHLACT; -.
DR   OrthoDB; 1288109at2759; -.
DR   PhylomeDB; A4IGF3; -.
DR   TreeFam; TF327014; -.
DR   PRO; PR:A4IGF3; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 4.
DR   Bgee; ENSDARG00000063686; Expressed in cardiac ventricle and 28 other tissues.
DR   GO; GO:0031314; C:extrinsic component of mitochondrial inner membrane; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0034982; P:mitochondrial protein processing; IBA:GO_Central.
DR   GO; GO:0033615; P:mitochondrial proton-transporting ATP synthase complex assembly; IBA:GO_Central.
DR   InterPro; IPR019165; Peptidase_M76_ATP23.
DR   PANTHER; PTHR21711; PTHR21711; 1.
DR   Pfam; PF09768; Peptidase_M76; 1.
DR   PROSITE; PS00142; ZINC_PROTEASE; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Metal-binding; Metalloprotease; Protease; Reference proteome.
FT   CHAIN           1..254
FT                   /note="Mitochondrial inner membrane protease ATP23 homolog"
FT                   /id="PRO_0000330346"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        134
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10095"
FT   BINDING         133
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000250"
FT   BINDING         137
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   254 AA;  28984 MW;  E149BA3D0659D582 CRC64;
     MAQSGAKAAD LSREPPGEQK PSPSSRQNEE DLGYNLYPER GSRLKKSTVE ESLFTFKHKC
     QLMLQFAMDT SPYAKLLLGA MKSSGCTVFK DRHFSCEDCD GTVSGGFDAA TSQIVLCQNN
     IHQQAHMNRV VTHELIHAFD HCRAQVDWFS NYRHLACSEI RAANLSGDCS FINEFSRFNF
     GLRKHHQECV RGRALRSILA VRRVSREEAE RVVDEVFDSC FNDHAPFGRI PHSKKDAKFA
     HRDFENRDRY YANL