PTD_ORYSJ
ID PTD_ORYSJ Reviewed; 248 AA.
AC Q6L5B5; Q6L570;
DT 13-NOV-2019, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=Protein PARTING DANCERS homolog {ECO:0000305};
DE Short=OsPTD {ECO:0000303|PubMed:31266799};
DE EC=3.1.-.- {ECO:0000305};
DE AltName: Full=Protein PARTING DANCERS homolog 1 {ECO:0000305};
DE Short=OsPTD1 {ECO:0000303|PubMed:30589140};
GN Name=PTD {ECO:0000303|PubMed:31266799};
GN Synonyms=PTD1 {ECO:0000303|PubMed:30589140};
GN OrderedLocusNames=Os05g0588200 {ECO:0000312|EMBL:BAF18387.1},
GN LOC_Os05g51060 {ECO:0000305};
GN ORFNames=OJ1007_H05.15 {ECO:0000312|EMBL:AAT44166.1},
GN OJ1115_D04.1 {ECO:0000312|EMBL:AAT37994.1},
GN OsJ_19727 {ECO:0000312|EMBL:EEE64870.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16261349; DOI=10.1007/s00438-005-0039-y;
RA Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J.,
RA Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F.,
RA Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.;
RT "A fine physical map of the rice chromosome 5.";
RL Mol. Genet. Genomics 274:337-345(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP FUNCTION, INTERACTION WITH SHOC1 AND HEI10, SUBCELLULAR LOCATION, TISSUE
RP SPECIFICITY, AND DISRUPTION PHENOTYPE.
RX PubMed=30589140; DOI=10.1111/tpj.14214;
RA Ren Y., Chen D., Li W., Zhou D., Luo T., Yuan G., Zeng J., Cao Y., He Z.,
RA Zou T., Deng Q., Wang S., Zheng A., Zhu J., Liang Y., Liu H., Wang L.,
RA Li P., Li S.;
RT "OsSHOC1 and OsPTD1 are essential for crossover formation during rice
RT meiosis.";
RL Plant J. 98:315-328(2019).
RN [8]
RP FUNCTION, INTERACTION WITH SHOC1 AND HEI10, SUBCELLULAR LOCATION, AND
RP DISRUPTION PHENOTYPE.
RX PubMed=31266799; DOI=10.1104/pp.19.00082;
RA Zhang J., Wang C., Higgins J.D., Kim Y.J., Moon S., Jung K.H., Qu S.,
RA Liang W.;
RT "A multiprotein complex regulates interference-sensitive crossover
RT formation in rice.";
RL Plant Physiol. 181:221-235(2019).
CC -!- FUNCTION: Essential for normal crossover (CO) formation during meiosis
CC (PubMed:30589140, PubMed:31266799). Essential component for the
CC formation of class I meiotic COs (PubMed:31266799). Interacts with
CC SHOC1, another meiotic component, to regulate CO formation, possibly by
CC stabilizing the recombination intermediates during meiosis
CC (PubMed:30589140, PubMed:31266799). PTD and SHOC1 may form transient
CC heterotrimeric or heterotetrametric complexes with HEI10 and/or ZIP4 to
CC promote class I COs formation (PubMed:31266799). Does not seem to be
CC involved in early meiotic recombination steps involving double-strand
CC break (DSB) formation, processing, and single-strand invasion
CC (PubMed:31266799). Does not seem to be involved in homologous pairing
CC or synaptonemal complex (SC) assembly (PubMed:31266799).
CC {ECO:0000269|PubMed:30589140, ECO:0000269|PubMed:31266799}.
CC -!- SUBUNIT: Interacts with SHOC1 (via C-terminus) (PubMed:30589140,
CC PubMed:31266799). Interacts with HEI10 (PubMed:31266799).
CC {ECO:0000269|PubMed:30589140, ECO:0000269|PubMed:31266799}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000269|PubMed:31266799}. Nucleus
CC {ECO:0000269|PubMed:30589140, ECO:0000269|PubMed:31266799}. Cytoplasm
CC {ECO:0000269|PubMed:30589140}. Cell membrane
CC {ECO:0000269|PubMed:30589140}. Note=Predominantly localized in the
CC nucleus (PubMed:30589140). Localized in punctuate foci onto meiocyte
CC chromosomes from leptotene to early pachytene with a maximal number of
CC foci at zygotene (PubMed:31266799). {ECO:0000269|PubMed:30589140,
CC ECO:0000269|PubMed:31266799}.
CC -!- TISSUE SPECIFICITY: Highly expressed in anthers and pistil during
CC meiosis (PubMed:30589140). Expressed in pollen mother cells (PMCs)
CC during meiosis (PubMed:30589140). Expressed at low levels in roots,
CC shoots, leaves, flowers, and glumes (PubMed:30589140).
CC {ECO:0000269|PubMed:30589140}.
CC -!- DISRUPTION PHENOTYPE: Complete sterility of male and female
CC gametophytes due to altered meiosis (PubMed:30589140, PubMed:31266799).
CC Striking reduction in the number of meiotic crossovers
CC (PubMed:30589140, PubMed:31266799). {ECO:0000269|PubMed:30589140,
CC ECO:0000269|PubMed:31266799}.
CC -!- SIMILARITY: Belongs to the ERCC1/RAD10/SWI10 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAT37994.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC098598; AAT44166.1; -; Genomic_DNA.
DR EMBL; AC105260; AAT37994.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008211; BAF18387.1; -; Genomic_DNA.
DR EMBL; AP014961; BAS95595.1; -; Genomic_DNA.
DR EMBL; CM000142; EEE64870.1; -; Genomic_DNA.
DR EMBL; AK109323; BAG98668.1; -; mRNA.
DR RefSeq; XP_015640256.1; XM_015784770.1.
DR AlphaFoldDB; Q6L5B5; -.
DR STRING; 4530.OS05T0588200-01; -.
DR PaxDb; Q6L5B5; -.
DR PRIDE; Q6L5B5; -.
DR EnsemblPlants; Os05t0588200-01; Os05t0588200-01; Os05g0588200.
DR GeneID; 4339770; -.
DR Gramene; Os05t0588200-01; Os05t0588200-01; Os05g0588200.
DR KEGG; osa:4339770; -.
DR eggNOG; ENOG502QRWT; Eukaryota.
DR HOGENOM; CLU_080281_0_0_1; -.
DR InParanoid; Q6L5B5; -.
DR OMA; REQNDSF; -.
DR OrthoDB; 1104615at2759; -.
DR Proteomes; UP000000763; Chromosome 5.
DR Proteomes; UP000007752; Chromosome 5.
DR Proteomes; UP000059680; Chromosome 5.
DR GO; GO:0005694; C:chromosome; IDA:UniProtKB.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0007140; P:male meiotic nuclear division; IEA:EnsemblPlants.
DR GO; GO:0048236; P:plant-type sporogenesis; IEA:EnsemblPlants.
DR GO; GO:0009555; P:pollen development; IEA:EnsemblPlants.
DR GO; GO:0010845; P:positive regulation of reciprocal meiotic recombination; IEA:EnsemblPlants.
DR GO; GO:0007131; P:reciprocal meiotic recombination; IMP:UniProtKB.
DR GO; GO:0000712; P:resolution of meiotic recombination intermediates; IEA:EnsemblPlants.
DR InterPro; IPR039172; PTD.
DR InterPro; IPR010994; RuvA_2-like.
DR PANTHER; PTHR37394; PTHR37394; 1.
DR SUPFAM; SSF47781; SSF47781; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Chromosome; Cytoplasm; DNA recombination; Endonuclease;
KW Hydrolase; Meiosis; Membrane; Nuclease; Nucleus; Reference proteome.
FT CHAIN 1..248
FT /note="Protein PARTING DANCERS homolog"
FT /id="PRO_0000448443"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 248 AA; 27850 MW; EE794046218D15E2 CRC64;
MERSTHSTGW TCLPPPPPEP AAPGRGVCAM STSWRDKQQP SLINFIAAFL AANSYRLNFL
SISPDFIFNN GELSVAFIFE TNWDCQNEGA VFSRVNMLKR QLKHLYVVVA VPTKEQNESF
NRSYHKYGMK LGFPTFVPVT DPEMGFEKIV KIAHALGVCK QQDIISRLKN EREQAVQCTD
SFLRVLTSIP GIDNHDANAL AQAIGSIEAI AKASKKFILE NTDLSTDKAE TIVRFFRDPQ
YYLSPKIN
