ID   PTER_XENLA              Reviewed;         349 AA.
AC   Q7SZS2;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Phosphotriesterase-related protein;
DE            EC=3.1.-.-;
DE   AltName: Full=Parathion hydrolase-related protein;
GN   Name=pter;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC         Evidence={ECO:0000250};
CC       Note=Binds 2 divalent metal cations per subunit. {ECO:0000250};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Phosphotriesterase family. {ECO:0000255|PROSITE-ProRule:PRU00679}.
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DR   EMBL; BC056120; AAH56120.1; -; mRNA.
DR   RefSeq; NP_001080454.1; NM_001086985.1.
DR   RefSeq; XP_018121761.1; XM_018266272.1.
DR   RefSeq; XP_018121762.1; XM_018266273.1.
DR   AlphaFoldDB; Q7SZS2; -.
DR   SMR; Q7SZS2; -.
DR   MaxQB; Q7SZS2; -.
DR   DNASU; 380146; -.
DR   GeneID; 380146; -.
DR   KEGG; xla:380146; -.
DR   CTD; 380146; -.
DR   Xenbase; XB-GENE-1007038; pter.L.
DR   OMA; MVKCGFI; -.
DR   OrthoDB; 972282at2759; -.
DR   Proteomes; UP000186698; Chromosome 6L.
DR   Bgee; 380146; Expressed in kidney and 19 other tissues.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009056; P:catabolic process; IEA:InterPro.
DR   CDD; cd00530; PTE; 1.
DR   InterPro; IPR017947; AryldialkylPase_Zn-BS.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   InterPro; IPR001559; Phosphotriesterase.
DR   PANTHER; PTHR10819; PTHR10819; 1.
DR   Pfam; PF02126; PTE; 1.
DR   PIRSF; PIRSF016839; PhP; 1.
DR   SUPFAM; SSF51556; SSF51556; 1.
DR   PROSITE; PS01322; PHOSPHOTRIESTERASE_1; 1.
DR   PROSITE; PS51347; PHOSPHOTRIESTERASE_2; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Metal-binding; Reference proteome.
FT   CHAIN           1..349
FT                   /note="Phosphotriesterase-related protein"
FT                   /id="PRO_0000388670"
FT   BINDING         26
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P45548"
FT   BINDING         28
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P45548"
FT   BINDING         169
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P45548"
FT   BINDING         169
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P45548"
FT   BINDING         201
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P45548"
FT   BINDING         230
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P45548"
FT   BINDING         298
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P45548"
SQ   SEQUENCE   349 AA;  38751 MW;  B40FC35B874EAD9F CRC64;
     MSSLSGKVQT VLGPIHSDQL GHTLTHEHLS MTFECCYCPP PAPQGALSDA PILMKNLFWV
     KQNPYSNKEN LLLNQEIDAI SEELKLFKAA GGGSIVENTT TGISRDVKML KKLAEETGVN
     IISGAGFYVD ATHSNSTRSM TVEQLTEVLV NEVLQGADGT NIKCGIIGEI GCSWPLTESE
     KKVLQATAEA QSQLGCPVNI HPGRNSDAPF QIIQILQEAG ADISKTVMSH LDRTIFDETK
     LLEFAKLGSY LEYDLFGTEM LNYQFNQAVD MPSDNDRIKM LRFLINEGYE DRIVVSHDIH
     TKNRLLKYGG HGYSHILNNI VPKMLIRGIS QQCIDKILLE NPKKWLTFK