位置:首页 > 蛋白库 > PTG3L_MOUSE
PTG3L_MOUSE
ID   PTG3L_MOUSE             Reviewed;         131 AA.
AC   Q9D9A7; Q9D0U4;
DT   05-SEP-2012, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=Putative protein PTGES3L;
DE   AltName: Full=Prostaglandin E synthase 3-like;
GN   Name=Ptges3l;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC   STRAIN=C57BL/6J; TISSUE=Embryo, and Testis;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q9D9A7-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q9D9A7-2; Sequence=VSP_044056;
CC   -!- SIMILARITY: Belongs to the p23/wos2 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AK004415; BAB23297.1; -; mRNA.
DR   EMBL; AK007198; BAB24896.1; -; mRNA.
DR   EMBL; AL590996; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL732315; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH466558; EDL34040.1; -; Genomic_DNA.
DR   EMBL; CH466558; EDL34041.1; -; Genomic_DNA.
DR   CCDS; CCDS25468.1; -. [Q9D9A7-1]
DR   RefSeq; NP_081141.1; NM_026865.2. [Q9D9A7-1]
DR   AlphaFoldDB; Q9D9A7; -.
DR   SMR; Q9D9A7; -.
DR   STRING; 10090.ENSMUSP00000099391; -.
DR   PhosphoSitePlus; Q9D9A7; -.
DR   PaxDb; Q9D9A7; -.
DR   PRIDE; Q9D9A7; -.
DR   Antibodypedia; 71718; 33 antibodies from 6 providers.
DR   DNASU; 73635; -.
DR   Ensembl; ENSMUST00000093933; ENSMUSP00000091465; ENSMUSG00000097487. [Q9D9A7-2]
DR   Ensembl; ENSMUST00000103102; ENSMUSP00000099391; ENSMUSG00000097487. [Q9D9A7-1]
DR   GeneID; 73635; -.
DR   KEGG; mmu:73635; -.
DR   UCSC; uc007lot.1; mouse. [Q9D9A7-1]
DR   CTD; 100885848; -.
DR   MGI; MGI:1916146; Ptges3l.
DR   VEuPathDB; HostDB:ENSMUSG00000097487; -.
DR   eggNOG; KOG3158; Eukaryota.
DR   GeneTree; ENSGT00940000163448; -.
DR   HOGENOM; CLU_078883_1_0_1; -.
DR   InParanoid; Q9D9A7; -.
DR   BioGRID-ORCS; 73635; 2 hits in 39 CRISPR screens.
DR   ChiTaRS; Ptges3l; mouse.
DR   PRO; PR:Q9D9A7; -.
DR   Proteomes; UP000000589; Chromosome 11.
DR   RNAct; Q9D9A7; protein.
DR   Bgee; ENSMUSG00000097487; Expressed in hindlimb stylopod muscle and 105 other tissues.
DR   ExpressionAtlas; Q9D9A7; baseline and differential.
DR   Genevisible; Q9D9A7; MM.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0051087; F:chaperone binding; IBA:GO_Central.
DR   GO; GO:0051879; F:Hsp90 protein binding; IBA:GO_Central.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; IBA:GO_Central.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR007052; CS_dom.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   InterPro; IPR045250; p23-like.
DR   PANTHER; PTHR22932; PTHR22932; 1.
DR   SUPFAM; SSF49764; SSF49764; 1.
DR   PROSITE; PS51203; CS; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..131
FT                   /note="Putative protein PTGES3L"
FT                   /id="PRO_0000418441"
FT   DOMAIN          3..91
FT                   /note="CS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00547"
FT   VAR_SEQ         127..131
FT                   /note="DDSDS -> MHTSHSTHEEIRRL (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:16141072"
FT                   /id="VSP_044056"
SQ   SEQUENCE   131 AA;  15652 MW;  08DD8BAAD0881823 CRC64;
     MERQPARTLW YDRPKYVFME FCVEDSTDVS VLIEDHRVVF SCRNGDGVEL YNEIEFYAKV
     NSKDSQDKRS GRSITCFVRK WKEKVAWPRL TKEDIKPVWL SVDFDNWRDW EGDDEVELAQ
     VEHYAEDDSD S
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024