ATP23_XENTR
ID ATP23_XENTR Reviewed; 235 AA.
AC Q5BKJ4;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-APR-2005, sequence version 1.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=Mitochondrial inner membrane protease ATP23 homolog;
DE EC=3.4.24.-;
GN Name=atp23; ORFNames=TEgg079g08.1;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Egg;
RG Sanger Xenopus tropicalis EST/cDNA project;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M76 family. {ECO:0000305}.
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DR EMBL; CR761179; CAJ82092.1; -; mRNA.
DR EMBL; BC091052; AAH91052.1; -; mRNA.
DR RefSeq; NP_001025602.1; NM_001030431.1.
DR AlphaFoldDB; Q5BKJ4; -.
DR STRING; 8364.ENSXETP00000032154; -.
DR MEROPS; M76.001; -.
DR PaxDb; Q5BKJ4; -.
DR DNASU; 594990; -.
DR Ensembl; ENSXETT00000032154; ENSXETP00000032154; ENSXETG00000014677.
DR GeneID; 594990; -.
DR KEGG; xtr:594990; -.
DR CTD; 91419; -.
DR Xenbase; XB-GENE-971247; atp23.
DR eggNOG; KOG3314; Eukaryota.
DR HOGENOM; CLU_079125_1_0_1; -.
DR InParanoid; Q5BKJ4; -.
DR OrthoDB; 1288109at2759; -.
DR PhylomeDB; Q5BKJ4; -.
DR Proteomes; UP000008143; Chromosome 3.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000014677; Expressed in egg cell and 13 other tissues.
DR ExpressionAtlas; Q5BKJ4; baseline.
DR GO; GO:0031314; C:extrinsic component of mitochondrial inner membrane; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0034982; P:mitochondrial protein processing; IBA:GO_Central.
DR GO; GO:0033615; P:mitochondrial proton-transporting ATP synthase complex assembly; IBA:GO_Central.
DR InterPro; IPR019165; Peptidase_M76_ATP23.
DR PANTHER; PTHR21711; PTHR21711; 1.
DR Pfam; PF09768; Peptidase_M76; 1.
DR PROSITE; PS00142; ZINC_PROTEASE; 1.
PE 2: Evidence at transcript level;
KW Hydrolase; Metal-binding; Metalloprotease; Protease; Reference proteome.
FT CHAIN 1..235
FT /note="Mitochondrial inner membrane protease ATP23 homolog"
FT /id="PRO_0000330348"
FT ACT_SITE 115
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU10095"
FT BINDING 114
FT /ligand="a divalent metal cation"
FT /ligand_id="ChEBI:CHEBI:60240"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000250"
FT BINDING 118
FT /ligand="a divalent metal cation"
FT /ligand_id="ChEBI:CHEBI:60240"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000250"
SQ SEQUENCE 235 AA; 26998 MW; A8EB220FF98FF921 CRC64;
MEEKKIEQDE LGYQLFPERG NGDRKKQGLL SKSLFTFNHK CQVMLKIALD TSPYAKLLLD
AMKHTGCTVY KDRHFSCEEC DGSVSGGFDA ATSEIVLCQN NIHQQSHMNR VVTHELIHAF
DHCRAHVDWF NNVRHLACSE IRAANLSGDC TLANELTRFK FGVKEHHKVC VRDRALRSIL
AVRNVSRETA EKAVDEVFDS CFNDHEPFGR IPHSKTDAKF AHRDFQNRDR YYANL