ID   ATP25_AJECH             Reviewed;         732 AA.
AC   C6HBY6;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   25-MAY-2022, entry version 29.
DE   RecName: Full=ATPase synthesis protein 25, mitochondrial;
DE   Flags: Precursor;
GN   Name=ATP25; ORFNames=HCDG_03535;
OS   Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=544712;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H143;
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA   Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA   Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA   Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA   Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain H143.";
RL   Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable mitochondrial mRNA stabilization factor.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATP25 family. {ECO:0000305}.
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DR   EMBL; GG692422; EER42076.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6HBY6; -.
DR   SMR; C6HBY6; -.
DR   STRING; 544712.C6HBY6; -.
DR   EnsemblFungi; EER42076; EER42076; HCDG_03535.
DR   VEuPathDB; FungiDB:HCDG_03535; -.
DR   HOGENOM; CLU_016140_0_0_1; -.
DR   OMA; IMIFGTA; -.
DR   Proteomes; UP000002624; Unassembled WGS sequence.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0140053; P:mitochondrial gene expression; IEA:InterPro.
DR   Gene3D; 3.30.460.10; -; 1.
DR   InterPro; IPR040152; Atp25.
DR   InterPro; IPR043519; NT_sf.
DR   PANTHER; PTHR28087; PTHR28087; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transit peptide.
FT   TRANSIT         1..52
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           53..732
FT                   /note="ATPase synthesis protein 25, mitochondrial"
FT                   /id="PRO_0000404455"
FT   REGION          355..393
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   732 AA;  82119 MW;  6A5AFD3C38A2D586 CRC64;
     MSRVLLRGIQ CHACRSNVIR SFISVSDVAI TPLAGGSRST AQARPPPLSR NFSSQHAKLF
     SNQPSDNAEL VVDPIPEIHT GEETEGQPEE SQEHIPWYLK EEQVEETIPH PLRKQQPLPP
     LPENPPPILE NLLEHISVDI GLDNLSLLDL RRLDPPPALG ANLIMIFGTA RGVKHLNVSA
     DRLCRWLRTT YKLRPDADGL LGRNELKIKL RRKARRAKLA KSAKSTLTQP DDGITTGWIC
     VDVGTVEGGQ FRKPEEELRK VGFVGFGTVV EGTRIVVQMM TEEKRQEIDL EGLWRQKLER
     NSLENEGLPQ PQAAAPQEAG DIHEQLTVPP TNISHQISHA TQISANYEQR RGISTGSRRY
     QDATSDTWGT SQISPNSETT HLEPSAPSSL TSLSHHFKNI PPHEAIYDLG QGTHDRCSTA
     FLQQFYQEVA RAPSELASSR RIELMCIAIE LHHPGYRKPD LFQAIQEHVL SNYALTRAQF
     LQILDAFLSF KPDLTSNPPR LLLPNADMEL ALQIIDHAGL RGLNLLDSTI LVKLFVGVSF
     RAQVYPVKEK DLPNSPVIGN RIPVPLNTCD AVKRVQSRLT RVKTAAKITF TTEQYMRILR
     VLFDQGSYSE FWNTWEDMAL AGIARDKALY VFLFQLHAES DGWQCFTTQL LNCIPMMERE
     NPPVHLDGEL AEVTQKCITI AYPEIIDRVE RNEQNPLVRM WHRCRVAIEN AAAAGGRGQD
     STAPYVCNHS DI