ID   ATP25_CANAL             Reviewed;         580 AA.
AC   Q59UH7; A0A1D8PSG6;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=ATPase synthesis protein 25, mitochondrial;
DE   Flags: Precursor;
GN   Name=ATP25; OrderedLocusNames=CAALFM_CR03350CA;
GN   ORFNames=CaO19.2387, CaO19.9923;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Probable mitochondrial mRNA stabilization factor.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATP25 family. {ECO:0000305}.
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DR   EMBL; CP017630; AOW31073.1; -; Genomic_DNA.
DR   RefSeq; XP_713220.1; XM_708127.1.
DR   AlphaFoldDB; Q59UH7; -.
DR   SMR; Q59UH7; -.
DR   STRING; 237561.Q59UH7; -.
DR   PRIDE; Q59UH7; -.
DR   GeneID; 3645142; -.
DR   KEGG; cal:CAALFM_CR03350CA; -.
DR   CGD; CAL0000179030; orf19.9923.
DR   VEuPathDB; FungiDB:CR_03350C_A; -.
DR   eggNOG; ENOG502RGZN; Eukaryota.
DR   HOGENOM; CLU_454918_0_0_1; -.
DR   InParanoid; Q59UH7; -.
DR   OrthoDB; 904950at2759; -.
DR   PRO; PR:Q59UH7; -.
DR   Proteomes; UP000000559; Chromosome R.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0004827; F:proline-tRNA ligase activity; NAS:CGD.
DR   GO; GO:0140053; P:mitochondrial gene expression; IEA:InterPro.
DR   GO; GO:0033615; P:mitochondrial proton-transporting ATP synthase complex assembly; IBA:GO_Central.
DR   GO; GO:0048255; P:mRNA stabilization; IBA:GO_Central.
DR   GO; GO:0006433; P:prolyl-tRNA aminoacylation; NAS:CGD.
DR   Gene3D; 3.30.460.10; -; 1.
DR   InterPro; IPR040152; Atp25.
DR   InterPro; IPR043519; NT_sf.
DR   PANTHER; PTHR28087; PTHR28087; 1.
DR   SUPFAM; SSF81301; SSF81301; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transit peptide.
FT   TRANSIT         1..38
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           39..580
FT                   /note="ATPase synthesis protein 25, mitochondrial"
FT                   /id="PRO_0000404463"
SQ   SEQUENCE   580 AA;  66837 MW;  9A4D7DC32218F147 CRC64;
     MIVRGKCLGR SVSKAVSLFS RPISVISAKS FATTTNLLQN SKDDSTEATI PWYMREENSS
     PVEVLNKIEV PELPENSPQS LQEFVTLLTV EYGLTDLEIF DLSQLPEDHP KSLEEQNEEN
     YVILASGKSE KHIYKAAYEL RLYIKHTYKH LPIIEGMSSN SISKVTRRRL AKRVRRGPPA
     TASTFGIGAN SWVSCGTGVD GIVIHLLSRE RRESLNLEQL YSDEQENEES HSTPEIDQDR
     LFFGDRRGFH TSSRNFNLNT LSNIYDSYVI DGNFDTSQKF KAQFDLNFKG GSVEEYNKKF
     ELYRAINLVN ANVVEANEIE QIIWDKYSSL DLALQQEIDW NTEIIKDTIK YMEFLVDLNA
     RHSPREKLDK LSGFISNITC FAGDSIDLFT IDKFGALLWR LTWVSENNNA LDSANLNEII
     KRKGDFEPGT NTISFDNELG RNIRELLRQN KYSSNKETFP LWLREQMMYT FGQAGLWDRF
     WRDWQSILQS LNKTNERIYF WVVTALFLSK VDNRDALRHL FTKYWSNPSG ASFVADYTTN
     NHQFNSDNER MALKSVLVQI GEKYNTSPWA REAAQFADNL