ID   ATP25_COCP7             Reviewed;         725 AA.
AC   C5PDQ4;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   25-MAY-2022, entry version 42.
DE   RecName: Full=ATPase synthesis protein 25, mitochondrial;
DE   Flags: Precursor;
GN   Name=ATP25; ORFNames=CPC735_018190;
OS   Coccidioides posadasii (strain C735) (Valley fever fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=222929;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C735;
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- FUNCTION: Probable mitochondrial mRNA stabilization factor.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATP25 family. {ECO:0000305}.
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DR   EMBL; ACFW01000043; EER25215.1; -; Genomic_DNA.
DR   RefSeq; XP_003067360.1; XM_003067314.1.
DR   AlphaFoldDB; C5PDQ4; -.
DR   SMR; C5PDQ4; -.
DR   PRIDE; C5PDQ4; -.
DR   EnsemblFungi; EER25215; EER25215; CPC735_018190.
DR   GeneID; 9692971; -.
DR   KEGG; cpw:CPC735_018190; -.
DR   VEuPathDB; FungiDB:CPC735_018190; -.
DR   HOGENOM; CLU_016140_0_0_1; -.
DR   Proteomes; UP000009084; Unassembled WGS sequence.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0140053; P:mitochondrial gene expression; IEA:InterPro.
DR   Gene3D; 3.30.460.10; -; 1.
DR   InterPro; IPR040152; Atp25.
DR   InterPro; IPR043519; NT_sf.
DR   PANTHER; PTHR28087; PTHR28087; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Transit peptide.
FT   TRANSIT         1..66
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           67..725
FT                   /note="ATPase synthesis protein 25, mitochondrial"
FT                   /id="PRO_0000404469"
FT   REGION          39..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          317..346
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        44..88
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   725 AA;  80627 MW;  D63A2A0B8BA831A6 CRC64;
     MHRLMLRGIQ CYGCRSHVIQ SFLAIADITF PAPRYHKPCP RSPLHHQSSF SSLHGQPFRG
     QSIARSASSG EPSVDNGSEQ SPDAASQSNE HVPWYLKEET AELASHPLGQ QQLIPPLPDN
     PPPMLEDLLQ HISVDIGLDD LSLLDLRNRN PPPALGANLI MIIGTARSVK HLNVAADRLC
     RWLRSTYKLQ PTADGLLGRN ELKIKLRRKA RRAKLSSNVS SSFEEKDDGI TTGWICVNVG
     SVENGKPAAG AQKRDFAGFG NVADSARIVV QMLTEEKRAE LDLEGLWNGN FPPRSPSELR
     AFEQQFEQFA EKAAAEATSG RGMYRDSRSH ATGSGIDPGQ RRGLHTSRRV QSISIEAVLS
     PGMVPRQEAA LNHEDHLVSP RNAPAKASKP LNVPPEITSL LQHLAQLPRD DALRELGSGP
     RDMGSTLFLR LFQQALDNAE DPDGNILAKL ELIRIAVTLQ HPQYTKADLF DAFKELAASG
     YDISESQALQ TVKTLLSFGD NDADVSNVAK RVLRSDIDLA LKVLNHMSLR GMDILSREVF
     SMLYTASGFQ VPVRPTNDNL SPSSVETEKS TPVSAEELNE VRLVQDRLRK IMDAFDVKFG
     PEQFLSLLRF HFHHGNYDQF WAIWRKMSLL QLPRSKEFYV LLFRLHAERG NQKRAAECLS
     SWVPMMAREQ PPVHLDADIA RVVMACLLVA NPDVKQRADA GDPGEYPNLW NRCWNALVAS
     QTVQE