ID   ATP25_KLULA             Reviewed;         562 AA.
AC   Q6CLH6;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=ATPase synthesis protein 25, mitochondrial;
DE   Flags: Precursor;
GN   Name=ATP25; OrderedLocusNames=KLLA0F02948g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Probable mitochondrial mRNA stabilization factor.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATP25 family. {ECO:0000305}.
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DR   EMBL; CR382126; CAG97921.1; -; Genomic_DNA.
DR   RefSeq; XP_455213.1; XM_455213.1.
DR   AlphaFoldDB; Q6CLH6; -.
DR   SMR; Q6CLH6; -.
DR   STRING; 28985.XP_455213.1; -.
DR   PRIDE; Q6CLH6; -.
DR   EnsemblFungi; CAG97921; CAG97921; KLLA0_F02948g.
DR   GeneID; 2895778; -.
DR   KEGG; kla:KLLA0_F02948g; -.
DR   eggNOG; ENOG502RGZN; Eukaryota.
DR   HOGENOM; CLU_557841_0_0_1; -.
DR   InParanoid; Q6CLH6; -.
DR   OMA; KISDFMV; -.
DR   Proteomes; UP000000598; Chromosome F.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0140053; P:mitochondrial gene expression; IEA:InterPro.
DR   GO; GO:0048255; P:mRNA stabilization; IEA:InterPro.
DR   Gene3D; 3.30.460.10; -; 1.
DR   InterPro; IPR040152; Atp25.
DR   InterPro; IPR025210; ATP25_mRNA_stabil_dom.
DR   InterPro; IPR043519; NT_sf.
DR   PANTHER; PTHR28087; PTHR28087; 1.
DR   Pfam; PF13929; mRNA_stabil; 1.
DR   SUPFAM; SSF81301; SSF81301; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transit peptide.
FT   TRANSIT         1..36
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           37..562
FT                   /note="ATPase synthesis protein 25, mitochondrial"
FT                   /id="PRO_0000404472"
SQ   SEQUENCE   562 AA;  65342 MW;  2CC9AA88D5F65F82 CRC64;
     MHRSYAVLLR NNVARLCYRP GSTLFIRNFT TRHSLRQSKP WYLDISENKE EDSNSPFIKP
     IRFPPTEIPA SLETISKYLN DKLAVTDIVV FDTAHSSSAT SIQSMASYVL IGTVKSFRHL
     QNCNDELIKF IKETFDEVPK SEGLVTSGIL RKRQRRLGRK TNLGKIAKIE NDESGWCLID
     SNVDGLFINI MTEERRDDLN LEELYCRVEE LDQYKKQINL NPPAEEEDDV LLGLRKLMMK
     NTKRYYSTVG ESPKPTFLEA LTIQDLDSAS KLIKEEKKPY HVIASALGRL PNHIELDAEN
     WIKLFNEATP TEGPLDYEYW GARFKFFQLL YISKRNNIEE NTQLDASTIK EFNRELNYFI
     NDFFRFKQLA LCQPTREELI GFLEICIQHL KLSKSYNQLI SVNMWILKAL QSYQYSDPKV
     VHDPRVIKLL VKSMHTENTN LNSLYEYVNL ITNEFEVRSL TNDVIKEIIT TLVESENWPT
     LFKFWKQCLC ESAVDSNVWD FFIKSLLNKN DKVILSDIVD NGHLLWIHRS KLVISDDLKA
     SLSKLLDRVD GSHTNIKKLL KL