ATP25_KOMPG
ID ATP25_KOMPG Reviewed; 634 AA.
AC C4QZ25;
DT 08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT 07-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 46.
DE RecName: Full=ATPase synthesis protein 25, mitochondrial;
DE Flags: Precursor;
GN Name=ATP25; OrderedLocusNames=PAS_chr1-4_0638;
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864;
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
CC -!- FUNCTION: Probable mitochondrial mRNA stabilization factor.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ATP25 family. {ECO:0000305}.
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DR EMBL; FN392319; CAY68499.1; -; Genomic_DNA.
DR RefSeq; XP_002490779.1; XM_002490734.1.
DR AlphaFoldDB; C4QZ25; -.
DR SMR; C4QZ25; -.
DR STRING; 644223.C4QZ25; -.
DR EnsemblFungi; CAY68499; CAY68499; PAS_chr1-4_0638.
DR GeneID; 8197846; -.
DR KEGG; ppa:PAS_chr1-4_0638; -.
DR eggNOG; ENOG502RGZN; Eukaryota.
DR HOGENOM; CLU_454918_0_0_1; -.
DR InParanoid; C4QZ25; -.
DR Proteomes; UP000000314; Chromosome 1.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140053; P:mitochondrial gene expression; IEA:InterPro.
DR GO; GO:0048255; P:mRNA stabilization; IEA:InterPro.
DR Gene3D; 3.30.460.10; -; 1.
DR InterPro; IPR040152; Atp25.
DR InterPro; IPR025210; ATP25_mRNA_stabil_dom.
DR InterPro; IPR043519; NT_sf.
DR PANTHER; PTHR28087; PTHR28087; 2.
DR Pfam; PF13929; mRNA_stabil; 2.
DR SUPFAM; SSF81301; SSF81301; 1.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Transit peptide.
FT TRANSIT 1..36
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 37..634
FT /note="ATPase synthesis protein 25, mitochondrial"
FT /id="PRO_0000404485"
SQ SEQUENCE 634 AA; 72342 MW; 25A8994251EDA925 CRC64;
MLRSLKPVTA FALKRSLLSI KQVHGTQSVL RSPVRNSSSI SSADEDPNLP WYLRTETKVA
KPIEMPELPE SSPQKLHELV KYFIKDLGIE DIKVFDLSMN EEEEVDGSKF LGKYMVIGTG
KSNKHLAKAG TEMMNFLKHE YGTPSSNIEG LVKDTLLIRQ QKRLKRKGGK LSSPQSNDFG
VSANSWIMID TNIDDIYVHF LTEKRRKELN LEYLWCSAED RPLYHQEVAT TQSDDIFSGI
RNYHTSSRTS RTYGVSRPQH LPSFTRSYSS TPSINELVHL SESGSYQEIS KFTNHNDPEV
TQLILLSHIN FFQNLPLNKA IAHADELYKS FEAAFPAFDA SSDHWKIRYL FLDMMHKVDK
SRWSFSIIEN NFYGKSSHGH RLTEEDLKYF IKSVIESPEL SNRYLDPNSN YDHDSTPFKD
EGSESFVSIS NNKLGKIAKF IQLCYPDLPE GNVFNHFESW DSTVLPLLLT VVSQTTHENF
ITPVKLSELS SPIANHKPVP YNKTHLDALL EVIRVSQPNF LLNDETRMNF IFILTILANA
HEWERVYKLW DAALENSVPI NPGSTFKPDT RPWAYLIDLV AKIGDPANAR VFLQKRWPQM
IHNGIDATDP KIGTATAVLL KVADPENVLF KNVK