ID   ATP25_LACTC             Reviewed;         620 AA.
AC   C5DGG6;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=ATPase synthesis protein 25, mitochondrial;
DE   Flags: Precursor;
GN   Name=ATP25; OrderedLocusNames=KLTH0D05170g;
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Probable mitochondrial mRNA stabilization factor.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATP25 family. {ECO:0000305}.
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DR   EMBL; CU928168; CAR22508.1; -; Genomic_DNA.
DR   RefSeq; XP_002552946.1; XM_002552900.1.
DR   AlphaFoldDB; C5DGG6; -.
DR   SMR; C5DGG6; -.
DR   STRING; 559295.C5DGG6; -.
DR   PRIDE; C5DGG6; -.
DR   EnsemblFungi; CAR22508; CAR22508; KLTH0D05170g.
DR   GeneID; 8295174; -.
DR   KEGG; lth:KLTH0D05170g; -.
DR   eggNOG; ENOG502RGZN; Eukaryota.
DR   HOGENOM; CLU_487522_0_0_1; -.
DR   InParanoid; C5DGG6; -.
DR   OMA; KISDFMV; -.
DR   OrthoDB; 904950at2759; -.
DR   Proteomes; UP000002036; Chromosome D.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0140053; P:mitochondrial gene expression; IEA:InterPro.
DR   GO; GO:0048255; P:mRNA stabilization; IEA:InterPro.
DR   Gene3D; 3.30.460.10; -; 1.
DR   InterPro; IPR040152; Atp25.
DR   InterPro; IPR025210; ATP25_mRNA_stabil_dom.
DR   InterPro; IPR043519; NT_sf.
DR   PANTHER; PTHR28087; PTHR28087; 1.
DR   Pfam; PF13929; mRNA_stabil; 1.
DR   SUPFAM; SSF81301; SSF81301; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..620
FT                   /note="ATPase synthesis protein 25, mitochondrial"
FT                   /id="PRO_0000404473"
FT   REGION          66..85
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..83
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   620 AA;  70435 MW;  02E5F92BCB868759 CRC64;
     MIERLILFNF QSDKNTKHTR VRNMLLRRAA AALPARKTPL HCYRRLGGSY RALSGSLLLR
     DEEKRLPHRV QDERDEAKAD TDLAADGDSA ATKPWYLNIV ERPAQNMPLH QQEIVFPANS
     PKSLETIATF LRDKLGLSDV LIFDLRDSQD EQVTAASKIS DFMVMATAKS GRHGHKSFIE
     LNTLLKQEFK TVGQVEGNIS ANELRRRQKR LARHTNLSKS MGSRTATTRS GSNLESWYMI
     DCRLDNIFVN ILTENKRQDL NLEELYAPPD QKHLYRREAP AEDVAPKEGD DNVLAGLKRL
     AARNQRRYFT TVPARVQIID ALSRQDFDLV LNVVSASKMD SLDILKAANQ TLRSMPYGVK
     IEGESWITFL DEVWPLAPYS QDFWSTRLEL FKLLNCAAPG QVNVDRVFTG YLKFKLASGE
     SLTKSDLVEF LQLVETNLSE NSHVDYEDLV AKNKCVLEAL KLYKGLDPRL ILDSEVMCLL
     LSTLSITQSG STSTLRAFYE MVEFASREFS QEPPVPVTAT VLRILADKQD YARILRFWEK
     SIASSPEKDH RPWPLFLDTV ASTGDQEFAK KVIRDGHLLW IKRNGVKASP ELREAIERLF
     AVADPAEVAF KDVKEFLTVE