ID   ATP25_PARBA             Reviewed;         728 AA.
AC   C1H741;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=ATPase synthesis protein 25, mitochondrial;
DE   Flags: Precursor;
GN   Name=ATP25; ORFNames=PAAG_06582;
OS   Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS   brasiliensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX   NCBI_TaxID=502779;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-826 / Pb01;
RX   PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA   Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA   Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA   Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA   Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA   Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA   Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA   Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA   Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT   "Comparative genomic analysis of human fungal pathogens causing
RT   paracoccidioidomycosis.";
RL   PLoS Genet. 7:E1002345-E1002345(2011).
CC   -!- FUNCTION: Probable mitochondrial mRNA stabilization factor.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATP25 family. {ECO:0000305}.
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DR   EMBL; KN294010; EEH35535.1; -; Genomic_DNA.
DR   RefSeq; XP_002791412.1; XM_002791366.2.
DR   AlphaFoldDB; C1H741; -.
DR   SMR; C1H741; -.
DR   EnsemblFungi; EEH35535; EEH35535; PAAG_06582.
DR   GeneID; 9094634; -.
DR   KEGG; pbl:PAAG_06582; -.
DR   VEuPathDB; FungiDB:PAAG_06582; -.
DR   eggNOG; ENOG502S5IB; Eukaryota.
DR   HOGENOM; CLU_016140_0_0_1; -.
DR   OMA; IMIFGTA; -.
DR   OrthoDB; 904950at2759; -.
DR   Proteomes; UP000002059; Partially assembled WGS sequence.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0140053; P:mitochondrial gene expression; IEA:InterPro.
DR   Gene3D; 3.30.460.10; -; 1.
DR   InterPro; IPR040152; Atp25.
DR   InterPro; IPR043519; NT_sf.
DR   PANTHER; PTHR28087; PTHR28087; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transit peptide.
FT   TRANSIT         1..29
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..728
FT                   /note="ATPase synthesis protein 25, mitochondrial"
FT                   /id="PRO_0000404478"
FT   REGION          65..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   728 AA;  81558 MW;  57FEA380E4FA22BE CRC64;
     MSRILLRGIQ CHACRQNVIR SFVSASGVTI TPPAIGSVST FNPHLSGSFP TRRVELFSSK
     AKDDSSLAAD SVSENSAAQE DSYPQENSQQ HVPWYLQEEL QEMAPHPMRQ QQELPPLPEN
     PPPILKVLLE YISADIGLDN LNLLDLRALD PPPALGANLI MIFGTARGVK HLNVSADRFC
     RWLRTTYKLR PDADGLLGRN ELKIKLRRKA RRAKLAKRAG STLTQPDDGI TTGWICVDVG
     IVEGGQLSKP EGVQKAGFVG FGTVVQGTRI VVQMMTEEKR EEIDLESLWR QTLEENSMEN
     QDLPKPQAEE PPQVVGFTHE PSTITTADFS HRISQTPPIR ANYEQLRSIS TSLHRLRDNR
     GPATDFVPTG TAAATKSAES NSSQVSLPSL FNYLSNLEPD KAIDELGQGV DDRTSTGFLQ
     KFYEELARAA PQIASTQRLE LMCTAILLQH SGYRKDNLFQ AFKEHIVSNY PLPRALVLRL
     LDALLAFKAD PNSNPPRLRL PSADMELALQ LIENAALRGA NIFHADFLIR VFLAVSYRTR
     VYAVKPENLH SAAITGNRIP VSIDEFESVQ RIQTRLASII RAAKVALGEK EYLDILRVHS
     NQGEYAKFWN AWGEVSLQGI HRGKSFYLFL FDLHAELGDW QQSRTTLLNC IPMMWREDPP
     IFFDAELAEA VSKCIALAYP DIDDRVQQNL PALIVKTWHR CRIAIQNQKM SERKERLIQA
     ELGTLPEN