ID   ATP25_PARBD             Reviewed;         731 AA.
AC   C1FZ15;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   04-FEB-2015, sequence version 2.
DT   25-MAY-2022, entry version 35.
DE   RecName: Full=ATPase synthesis protein 25, mitochondrial;
DE   Flags: Precursor;
GN   Name=ATP25; ORFNames=PADG_01041;
OS   Paracoccidioides brasiliensis (strain Pb18).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX   NCBI_TaxID=502780;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pb18;
RX   PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA   Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA   Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA   Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA   Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA   Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA   Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA   Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA   Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT   "Comparative genomic analysis of human fungal pathogens causing
RT   paracoccidioidomycosis.";
RL   PLoS Genet. 7:E1002345-E1002345(2011).
CC   -!- FUNCTION: Probable mitochondrial mRNA stabilization factor.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATP25 family. {ECO:0000305}.
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DR   EMBL; KN275957; EEH44752.2; -; Genomic_DNA.
DR   RefSeq; XP_010756096.1; XM_010757794.1.
DR   AlphaFoldDB; C1FZ15; -.
DR   SMR; C1FZ15; -.
DR   EnsemblFungi; EEH44752; EEH44752; PADG_01041.
DR   GeneID; 22580780; -.
DR   KEGG; pbn:PADG_01041; -.
DR   VEuPathDB; FungiDB:PADG_01041; -.
DR   eggNOG; ENOG502S5IB; Eukaryota.
DR   HOGENOM; CLU_016140_0_0_1; -.
DR   OMA; IMIFGTA; -.
DR   Proteomes; UP000001628; Unassembled WGS sequence.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0140053; P:mitochondrial gene expression; IEA:InterPro.
DR   Gene3D; 3.30.460.10; -; 1.
DR   InterPro; IPR040152; Atp25.
DR   InterPro; IPR043519; NT_sf.
DR   PANTHER; PTHR28087; PTHR28087; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transit peptide.
FT   TRANSIT         1..29
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..731
FT                   /note="ATPase synthesis protein 25, mitochondrial"
FT                   /id="PRO_0000404479"
FT   REGION          68..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        75..93
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   731 AA;  81800 MW;  F544FB0C7502566C CRC64;
     MSRVLLRGIQ CHACRQNVIR SFVSASGVTI TPPAIGSVSP SKAHPPHLSG SFPTRHVKLF
     SSQAKDDPSL AADAVSENSA AQEGSYPQEN SEQHVPWYLQ EEVQEMALHP MRQQQELPPL
     PENPPPILKV LLEYISVDIG LDNLNLLDLR TLDPPPALGA NLIMIFGTAR SVKHLNVSAD
     KFCRWLRTTY KLRPDADGLL GRNELKIKLR RKARRARLIK RAGSTLKQPD DGITTGWICV
     DVGIVEGGQL SKPEGVQKAG FVGFGTVIQG TRIVVQMMTE EKREEIDLES LWRQTLEKNS
     MDNPGLPKPQ AEEPPQVVGF THESSTVTAA DFSHRVSQTP PIRANYEQLR SISTSLHRLR
     DKRGSATDFV PTDTTVATKS AKSTSSQESL PSLFNYLSNL EPDKAIDELG QGMDDRTSTS
     FLQRFYEELA RTAPQIASAQ KLELMCTAIL LQHSGYRKED LFQAFKEHIV SNYPLPRALV
     LRILDALLAF KPDPNSNPPR LRLPGADMEL ALRLIENAAL RGTNILHADF LIRVFLAVSY
     RTRVYAVKPG NLHSAAITGN RIPVSIDEFE SVQRIQTRLA SIIRAAKVAL GEKEYLDILR
     VHSDQGEYAK FWNAWGEVAL AGIHRGKSFY LFLFNLHAEL GDWQQSRTTL LNCIPMMWRE
     DPPVFFDAEL AEVVSKCIAL AYPDIDDTVQ HNLPALIVKT WHHCRTAIQN QKMNERKERL
     IQTELGTLPE N