ID   ATP25_PARBP             Reviewed;         731 AA.
AC   C0S4K1;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   04-FEB-2015, sequence version 2.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=ATPase synthesis protein 25, mitochondrial;
DE   Flags: Precursor;
GN   Name=ATP25; ORFNames=PABG_02606;
OS   Paracoccidioides brasiliensis (strain Pb03).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX   NCBI_TaxID=482561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pb03;
RX   PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA   Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA   Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA   Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA   Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA   Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA   Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA   Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA   Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT   "Comparative genomic analysis of human fungal pathogens causing
RT   paracoccidioidomycosis.";
RL   PLoS Genet. 7:E1002345-E1002345(2011).
CC   -!- FUNCTION: Probable mitochondrial mRNA stabilization factor.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATP25 family. {ECO:0000305}.
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DR   EMBL; KN305533; EEH20347.2; -; Genomic_DNA.
DR   AlphaFoldDB; C0S4K1; -.
DR   SMR; C0S4K1; -.
DR   PRIDE; C0S4K1; -.
DR   EnsemblFungi; EEH20347; EEH20347; PABG_02606.
DR   VEuPathDB; FungiDB:PABG_02606; -.
DR   HOGENOM; CLU_016140_0_0_1; -.
DR   InParanoid; C0S4K1; -.
DR   Proteomes; UP000002740; Unassembled WGS sequence.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0140053; P:mitochondrial gene expression; IEA:InterPro.
DR   Gene3D; 3.30.460.10; -; 1.
DR   InterPro; IPR040152; Atp25.
DR   InterPro; IPR043519; NT_sf.
DR   PANTHER; PTHR28087; PTHR28087; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Transit peptide.
FT   TRANSIT         1..29
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..731
FT                   /note="ATPase synthesis protein 25, mitochondrial"
FT                   /id="PRO_0000404480"
FT   REGION          68..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        75..93
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   731 AA;  81918 MW;  C7670815F78E7BBB CRC64;
     MSRILLRGIQ CHACRQNVIR SFVSASGVTI TPPAIGSVSP SKAHPPHLSG SFPTRHVKLF
     SSQAKDDPSL AADAVSENSA AQEGSYPQEN SEQHVPWYLQ EEVQEMALHP MRQQQELPPL
     PENPPPILKV LLEYISFDIG LDNLNLLDLR TLDPPPALGA NLIMIFGTAR SVKHLNVSAD
     KFCRWLRTTY KLRPDADGLL GRNELKIKLR RKARRARLVK RAGSTLKQPD DGITTGWICV
     DVGIVEGGQL SKPEGVQKAG FVGFGTVIQG TRIVVQMMTE EKREEIDLES LWRQTLEKNS
     MDNPGLPKPQ AEEPPQVVGF THESSTVTAA DFSHRVSQTP PIRANYEQLR SISTSLHRLR
     DKRGSATDFV PTDTTVATKS AKSISSQESL PSLFNYLSNL EPDKAIDELG QGMDDRTSTS
     FLQRFYEELA RTAPQIASAQ KLELMCTGIL LQHSGYRKED LFQAFKEHIV SNYPLPRALV
     LRLLDALLAF KPDPNSNPPR LRLPGADMEL ALRLIENAAL RGTNILHADF LIRVFLAVSY
     RTRVYAVKPE NLHSAAITGN RIPVSIDEFE SVQRIQTRLA SIIRAAKVAL GEKEYLDILR
     VHSDQGEYAK FWNAWGEVAL AGIHRGKSFY LFLFNLHAEL GDWQQSRTTL LNCIPMMWRE
     DPPVFFDAEL AEVVSKCIAL AYPDIDDTVQ HNLPALIVKT WHHCRTAIQN QKMNERKERL
     IQTELGTLPE N