ID   PTIP2_HUMAN             Reviewed;         154 AA.
AC   P0DTF9;
DT   10-FEB-2021, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2021, sequence version 1.
DT   03-AUG-2022, entry version 6.
DE   RecName: Full=PTTG1IP family member 2 {ECO:0000305};
DE   Flags: Precursor;
GN   Name=PTTG1IP2 {ECO:0000312|HGNC:HGNC:55318};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K.,
RA   Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A.,
RA   Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H.,
RA   Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A.,
RA   Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P.,
RA   Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M.,
RA   Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S.,
RA   Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R.,
RA   Strowmatt C., Latreille P., Miller N., Johnson D., Murray J.,
RA   Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W.,
RA   Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A.,
RA   Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E.,
RA   Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A.,
RA   Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A.,
RA   Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R.,
RA   McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H.,
RA   Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass type I
CC       membrane protein {ECO:0000255}.
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DR   EMBL; AC002456; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF458505; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_016868378.1; XM_017012889.1.
DR   RefSeq; XP_016885904.1; XM_017030415.1.
DR   AlphaFoldDB; P0DTF9; -.
DR   SMR; P0DTF9; -.
DR   PeptideAtlas; P0DTF9; -.
DR   Ensembl; ENST00000509356.2; ENSP00000504097.1; ENSG00000251154.2.
DR   MANE-Select; ENST00000509356.2; ENSP00000504097.1; NM_001365443.2; NP_001352372.1.
DR   GeneCards; PTTG1IP2; -.
DR   HGNC; HGNC:55318; PTTG1IP2.
DR   neXtProt; NX_P0DTF9; -.
DR   GeneTree; ENSGT00390000004977; -.
DR   OMA; RCIWCRE; -.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000251154; Expressed in right testis and 7 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..154
FT                   /note="PTTG1IP family member 2"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000452020"
FT   TOPO_DOM        27..97
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        119..154
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   154 AA;  18282 MW;  916E55161F5C7338 CRC64;
     MCWLRAWGQI LLPVFLSLFL IQLLISFSEN GFIHSPRNNQ KPRDGNEEEC AVKKSCQLCT
     EDKKCVWCSE EKACKKYCFP YFGCRFSSIY WLNCKVDMFG IMMLLLIAVL ITGFVWYCCA
     YHFYLQDLNR NRVYFYGRRE TVPIHDRSAT VYDE