ID   PTIP2_MOUSE             Reviewed;         150 AA.
AC   D3YUK8;
DT   10-FEB-2021, integrated into UniProtKB/Swiss-Prot.
DT   20-APR-2010, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=PTTG1IP family member 2 {ECO:0000305};
DE   Flags: Precursor;
GN   Name=Pttg1ip2 {ECO:0000312|MGI:MGI:2686532};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass type I
CC       membrane protein {ECO:0000255}.
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DR   EMBL; AC068663; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS51410.1; -.
DR   RefSeq; NP_001186954.1; NM_001200025.1.
DR   AlphaFoldDB; D3YUK8; -.
DR   SMR; D3YUK8; -.
DR   GlyGen; D3YUK8; 1 site.
DR   PaxDb; D3YUK8; -.
DR   PRIDE; D3YUK8; -.
DR   Ensembl; ENSMUST00000115447; ENSMUSP00000111107; ENSMUSG00000079666.
DR   GeneID; 381716; -.
DR   KEGG; mmu:381716; -.
DR   UCSC; uc008wio.2; mouse.
DR   CTD; 102723899; -.
DR   MGI; MGI:2686532; Pttg1ip2.
DR   VEuPathDB; HostDB:ENSMUSG00000079666; -.
DR   eggNOG; ENOG502T3TA; Eukaryota.
DR   GeneTree; ENSGT00390000004977; -.
DR   HOGENOM; CLU_1901122_0_0_1; -.
DR   InParanoid; D3YUK8; -.
DR   OMA; RCIWCRE; -.
DR   OrthoDB; 1500852at2759; -.
DR   PhylomeDB; D3YUK8; -.
DR   BioGRID-ORCS; 381716; 2 hits in 72 CRISPR screens.
DR   Proteomes; UP000000589; Chromosome 5.
DR   RNAct; D3YUK8; protein.
DR   Bgee; ENSMUSG00000079666; Expressed in spermatid and 22 other tissues.
DR   ExpressionAtlas; D3YUK8; baseline and differential.
DR   Genevisible; D3YUK8; MM.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..150
FT                   /note="PTTG1IP family member 2"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000452021"
FT   TOPO_DOM        20..98
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        120..150
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   CARBOHYD        26
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   150 AA;  18023 MW;  97152852B8045706 CRC64;
     MCWLRAWSHI LLPVFLSVAL IQLIFNLSDH KTKTHHHWKR KIEAKYVEKE CAQKETCPVC
     TRDKRCIWCR EEKVCKKYCF PYSDCKFNSI FWANCNVDLF GIVMLILIVI LALAFLWYCL
     AYYFYMQQHM ALYARHGQVP VYNWDAPGDW