ID   PTMA_PELLE              Reviewed;         109 AA.
AC   Q90ZK2;
DT   15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Prothymosin alpha;
DE            Short=Prot-alpha;
OS   Pelophylax lessonae (Pool frog) (Rana lessonae).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Pelophylax.
OX   NCBI_TaxID=45623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Testis;
RX   PubMed=11744386; DOI=10.1016/s0925-4773(01)00569-x;
RA   Aniello F., Branno M., De Rienzo G., Ferrara D., Palmiero C., Minucci S.;
RT   "First evidence of prothymosin in a non-mammalian vertebrate and its
RT   involvement in the spermatogenesis of the frog Rana esculenta.";
RL   Mech. Dev. 110:213-217(2002).
CC   -!- FUNCTION: May have role in testicular activity.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Highly expressed in the testis.
CC   -!- DEVELOPMENTAL STAGE: Expression peaks in September/October in
CC       concomitance with germ cell maturation.
CC   -!- SIMILARITY: Belongs to the pro/parathymosin family. {ECO:0000305}.
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DR   EMBL; AJ312835; CAC39397.1; -; mRNA.
DR   AlphaFoldDB; Q90ZK2; -.
DR   SMR; Q90ZK2; -.
DR   PRIDE; Q90ZK2; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR004931; Pro/parathymosin.
DR   PANTHER; PTHR22745; PTHR22745; 1.
DR   Pfam; PF03247; Prothymosin; 1.
PE   2: Evidence at transcript level;
KW   Nucleus.
FT   CHAIN           1..109
FT                   /note="Prothymosin alpha"
FT                   /id="PRO_0000191629"
FT   REGION          1..109
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..41
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        44..79
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   109 AA;  11906 MW;  F1049EA0B5BC5BD9 CRC64;
     MSDTSVDASV EKTTKDLKSK DKELVEETEN GKDKPANGNA ENEENGEDGA DNEEEEEVDE
     EDEEDEGEGD DDEGDEDDEA DGATGKRAAE DDDEDDDVDA KKQKTDDDD