ID   PTP2_ENCHE              Reviewed;         272 AA.
AC   P0CAT5;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   25-MAY-2022, entry version 17.
DE   RecName: Full=Polar tube protein 2;
DE   Flags: Precursor;
GN   Name=PTP2;
OS   Encephalitozoon hellem (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC   Encephalitozoon.
OX   NCBI_TaxID=27973;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11159998; DOI=10.1128/iai.69.2.1016-1024.2001;
RA   Delbac F., Peuvel I., Metenier G., Peyretaillade E., Vivares C.P.;
RT   "Microsporidian invasion apparatus: identification of a novel polar tube
RT   protein and evidence for clustering of ptp1 and ptp2 genes in three
RT   Encephalitozoon species.";
RL   Infect. Immun. 69:1016-1024(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Vivares C.P., Danchin A., Delbac F.;
RT   "Microsporidium polar tube proteins, nucleic acids coding for said proteins
RT   and their uses.";
RL   Patent number WO0001724, 13-JAN-2000.
CC   -!- FUNCTION: Involved in formation of a polar tube through which the
CC       infectious agent is passed on to the host cell. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Spore polar tube {ECO:0000250}.
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DR   EMBL; AX007053; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P0CAT5; -.
DR   VEuPathDB; MicrosporidiaDB:EHEL_060160; -.
DR   VEuPathDB; MicrosporidiaDB:KMI_03g04590; -.
DR   GO; GO:0044099; C:polar tube; IEA:UniProtKB-SubCell.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR031507; PTP2.
DR   Pfam; PF17022; PTP2; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Signal; Sporulation.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..272
FT                   /note="Polar tube protein 2"
FT                   /id="PRO_0000377527"
FT   REGION          231..272
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        233..247
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        248..272
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        134
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   272 AA;  29342 MW;  6E43CF7CDAC5A873 CRC64;
     MLLLFTVVTL VSAAQVAPVT PQAAVPTQFL PGAQQKIGGV DNRCANKQVE GVQIFQGDMA
     DCPKRNSEAA NAMVQRAKQK ALEIYNKEIS KGPTPKDSGQ CIERAVQGTD RCILAKIIDK
     AVNMLKYRIS KVGNATALFR GNKLISLILN VDYGLKPFFT VVKKKTKRVF PQGDELNFNG
     IGQLIGVKGT FPQDNNDECK PCDSPKKTVE TVAEECNLGC QLKGTPGLIS RAIQKKEVKE
     SSKDGEKSST QNGEGTTDDE DGQQSPDGNG PE