ID   PTP2_ENCIN              Reviewed;         275 AA.
AC   P0CAT4;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   25-MAY-2022, entry version 19.
DE   RecName: Full=Polar tube protein 2;
DE   Flags: Precursor;
GN   Name=PTP2;
OS   Encephalitozoon intestinalis (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC   Encephalitozoon.
OX   NCBI_TaxID=58839;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11159998; DOI=10.1128/iai.69.2.1016-1024.2001;
RA   Delbac F., Peuvel I., Metenier G., Peyretaillade E., Vivares C.P.;
RT   "Microsporidian invasion apparatus: identification of a novel polar tube
RT   protein and evidence for clustering of ptp1 and ptp2 genes in three
RT   Encephalitozoon species.";
RL   Infect. Immun. 69:1016-1024(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Vivares C.P., Danchin A., Delbac F.;
RT   "Microsporidium polar tube proteins, nucleic acids coding for said proteins
RT   and their uses.";
RL   Patent number WO0001724, 13-JAN-2000.
CC   -!- FUNCTION: Involved in formation of a polar tube through which the
CC       infectious agent is passed on to the host cell. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Spore polar tube {ECO:0000250}.
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DR   EMBL; AX007052; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P0CAT4; -.
DR   VEuPathDB; MicrosporidiaDB:Eint_060140; -.
DR   GO; GO:0044099; C:polar tube; IEA:UniProtKB-SubCell.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR031507; PTP2.
DR   Pfam; PF17022; PTP2; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Signal; Sporulation.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..275
FT                   /note="Polar tube protein 2"
FT                   /id="PRO_0000377526"
FT   REGION          233..275
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        233..254
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        132
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        248
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   275 AA;  29919 MW;  527B307C011ED3DC CRC64;
     MLLLLSAVAF VSATAVQSGV VSQPTTPIPI LPGQPMGGMA NGCTNKKLDG VEIMRRNMVE
     CQKRNAEATK AMVERANEKA VETFNKEVSK GPQKESGQCI EKAVQGTDRC ILAGIIDKAV
     NKRKYRISDV ENSTSLYRGD KLIALIVNVD YGLQPIIKPK KKKSKIMANL PQPKREMYFN
     QIGQLVGAKG TFPQDNKDEC KPCEPKKTVE TASERCNLGC ELKGTSALIS KAIQKKEIKE
     SPKEGDRNTT QEYDGEGSAE DAEGQQPSAD GEGLE