ID   PTPJ2_MDBVW             Reviewed;         297 AA.
AC   Q5I139;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 49.
DE   RecName: Full=Probable tyrosine phosphatase protein J2;
DE            Short=PTP-J2;
DE            EC=3.1.3.48;
GN   Name=J3;
OS   Microplitis demolitor bracovirus (isolate Webb) (MdBV).
OC   Viruses; Polydnaviridae; Bracovirus.
OX   NCBI_TaxID=654919;
OH   NCBI_TaxID=69319; Microplitis demolitor.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=16380146; DOI=10.1016/j.virol.2005.11.010;
RA   Webb B.A., Strand M.R., Dickey S.E., Beck M.H., Hilgarth R.S., Barney W.E.,
RA   Kadash K., Kroemer J.A., Lindstrom K.G., Rattanadechakul W., Shelby K.S.,
RA   Thoetkiattikul H., Turnbull M.W., Witherell R.A.;
RT   "Polydnavirus genomes reflect their dual roles as mutualists and
RT   pathogens.";
RL   Virology 347:160-174(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:10684, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC         COMP:10137, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:46858,
CC         ChEBI:CHEBI:82620; EC=3.1.3.48;
CC   -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY875686; AAW51793.1; -; Genomic_DNA.
DR   RefSeq; YP_239389.1; NC_007036.1.
DR   SMR; Q5I139; -.
DR   GeneID; 5075822; -.
DR   KEGG; vg:5075822; -.
DR   Proteomes; UP000008168; Genome.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006470; P:protein dephosphorylation; IEA:InterPro.
DR   Gene3D; 3.90.190.10; -; 1.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR000242; PTP_cat.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   Pfam; PF00102; Y_phosphatase; 1.
DR   PRINTS; PR00700; PRTYPHPHTASE.
DR   SMART; SM00194; PTPc; 1.
DR   SMART; SM00404; PTPc_motif; 1.
DR   SUPFAM; SSF52799; SSF52799; 1.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Protein phosphatase; Reference proteome.
FT   CHAIN           1..297
FT                   /note="Probable tyrosine phosphatase protein J2"
FT                   /id="PRO_0000405356"
FT   DOMAIN          21..286
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00160"
FT   ACT_SITE        227
FT                   /note="Phosphocysteine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00160"
SQ   SEQUENCE   297 AA;  34458 MW;  092EE3801466E015 CRC64;
     MPIEDKRMRI MDFINFVRKP DSLSCIIQEY RAIVPEQEDG ASKSCNQAVN RAQDENNALP
     IVRLVHSRVN LFSKEKVMSA RYVDGYNHKQ KFIITINSCE NNTDKYLQML WDNNVQIVVT
     TSSHAEKNNF NRFWSLNERT VITYNNFQIE TLEIITKPHF VLTLLVLTDQ KGQARKLSHF
     QYTAWPADGF SHDPKAFLDF FFNIDSLYAD LRKHKTIGNV GPITIDCIDN NSSSEVFCVL
     DICLTEVKKT GMLSIANAVK KVRQKKYGCM NRLNDYVFCY HLIHAYLSMT FDIVKVR