PTR29_ARATH
ID PTR29_ARATH Reviewed; 521 AA.
AC O80436;
DT 02-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Protein NRT1/ PTR FAMILY 5.5;
DE Short=AtNPF5.5;
GN Name=NPF5.5; OrderedLocusNames=At2g38100; ORFNames=F16M14.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP TISSUE SPECIFICITY, AND GENE FAMILY.
RX PubMed=17481610; DOI=10.1016/j.febslet.2007.04.047;
RA Tsay Y.F., Chiu C.C., Tsai C.B., Ho C.H., Hsu P.K.;
RT "Nitrate transporters and peptide transporters.";
RL FEBS Lett. 581:2290-2300(2007).
RN [4]
RP GENE FAMILY.
RX PubMed=20501909; DOI=10.1105/tpc.110.075242;
RA Li J.Y., Fu Y.L., Pike S.M., Bao J., Tian W., Zhang Y., Chen C.Z.,
RA Zhang Y., Li H.M., Huang J., Li L.G., Schroeder J.I., Gassmann W.,
RA Gong J.M.;
RT "The Arabidopsis nitrate transporter NRT1.8 functions in nitrate removal
RT from the xylem sap and mediates cadmium tolerance.";
RL Plant Cell 22:1633-1646(2010).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=24055139; DOI=10.1016/j.tplants.2013.08.008;
RA Leran S., Varala K., Boyer J.C., Chiurazzi M., Crawford N.,
RA Daniel-Vedele F., David L., Dickstein R., Fernandez E., Forde B.,
RA Gassmann W., Geiger D., Gojon A., Gong J.M., Halkier B.A., Harris J.M.,
RA Hedrich R., Limami A.M., Rentsch D., Seo M., Tsay Y.F., Zhang M.,
RA Coruzzi G., Lacombe B.;
RT "A unified nomenclature of NITRATE TRANSPORTER 1/PEPTIDE TRANSPORTER family
RT members in plants.";
RL Trends Plant Sci. 19:5-9(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in roots. {ECO:0000269|PubMed:17481610}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Proton-
CC dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
CC {ECO:0000305}.
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DR EMBL; AC003028; AAC27159.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09489.1; -; Genomic_DNA.
DR PIR; T01242; T01242.
DR RefSeq; NP_181345.1; NM_129366.1.
DR AlphaFoldDB; O80436; -.
DR SMR; O80436; -.
DR STRING; 3702.AT2G38100.1; -.
DR PaxDb; O80436; -.
DR PRIDE; O80436; -.
DR EnsemblPlants; AT2G38100.1; AT2G38100.1; AT2G38100.
DR GeneID; 818388; -.
DR Gramene; AT2G38100.1; AT2G38100.1; AT2G38100.
DR KEGG; ath:AT2G38100; -.
DR Araport; AT2G38100; -.
DR TAIR; locus:2042937; AT2G38100.
DR eggNOG; KOG1237; Eukaryota.
DR HOGENOM; CLU_009313_4_1_1; -.
DR InParanoid; O80436; -.
DR PhylomeDB; O80436; -.
DR PRO; PR:O80436; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O80436; baseline and differential.
DR Genevisible; O80436; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR000109; POT_fam.
DR PANTHER; PTHR11654; PTHR11654; 1.
DR Pfam; PF00854; PTR2; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..521
FT /note="Protein NRT1/ PTR FAMILY 5.5"
FT /id="PRO_0000399963"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 310..327
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 356..376
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 394..414
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 440..460
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 478..498
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 521 AA; 57843 MW; 0A93E652354ACCB5 CRC64;
MSVLSWAFTV AWFTLWMLML YLTNEMKLKF TDAAAIVNVF AGVSAIGHLG MQFLVDAFIG
HFWMLCLSTL AFSFGFGFLA ISASPILSGN GQKGLFYVAL TVISVGIFGR SISLGVFTED
QLEDGRNKGN PAKLVSFVIG NVGNFVFLLL AAIAMPQISP WFVRFTIPSG CEVLAMLIFI
SGACSYKRVK PGGSPLTTVF RVFMASASKM SCAYSNNSSQ LYEKAECDQD IKPHTSSLRY
LDRAAMILQT ESLEQQRKNR WKLCRVTEVE QTKSVIRTVP LFATSLISGI VFSLGNTFFL
EQANHMDSKF GSWNLPLPLL LLFSEAARLG SRELCVMAAK RHAIDFPESP KQTKTPYGIP
VSIILSIFCC SIAAHVESRR LKVVSTQGLL HETVPMSVFW LLPQYILLGS ITGIYENSFA
LYLEETVPEE LSQYMVLLNV GVCGVGIMSN IALVSLVGSV SGGKWFQDTI NKSRVDNYYW
VITVFCMFNL LLYFIVTYRY TVCNKKDGAT QENDRRIIAS V