ID   PTR2_CANAX              Reviewed;         623 AA.
AC   P46030;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Peptide transporter PTR2;
GN   Name=PTR2;
OS   Candida albicans (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=5476;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 18804 / CBS 562 / JCM 1542 / NBRC 1385 / NRRL Y-12983;
RX   PubMed=7773409; DOI=10.1099/13500872-141-5-1147;
RA   Basrai M.A., Lubkowitz M.A., Perry J.R., Miller D., Krainer E.,
RA   Naider F.R., Becker J.M.;
RT   "Cloning of a Candida albicans peptide transport gene.";
RL   Microbiology 141:1147-1156(1995).
CC   -!- FUNCTION: Uptake of small peptides.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Proton-
CC       dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
CC       {ECO:0000305}.
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DR   EMBL; U09781; AAA80167.1; -; Genomic_DNA.
DR   AlphaFoldDB; P46030; -.
DR   SMR; P46030; -.
DR   VEuPathDB; FungiDB:CAWG_01534; -.
DR   VEuPathDB; FungiDB:CR_01830C_A; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006857; P:oligopeptide transport; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR000109; POT_fam.
DR   InterPro; IPR018456; PTR2_symporter_CS.
DR   PANTHER; PTHR11654; PTHR11654; 1.
DR   Pfam; PF00854; PTR2; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS01022; PTR2_1; 1.
DR   PROSITE; PS01023; PTR2_2; 1.
PE   3: Inferred from homology;
KW   Membrane; Peptide transport; Protein transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..623
FT                   /note="Peptide transporter PTR2"
FT                   /id="PRO_0000064318"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        163..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        250..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        277..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        385..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        418..438
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        448..468
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        499..519
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        529..549
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        557..577
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          31..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   623 AA;  69942 MW;  1601FD3AE21B80EB CRC64;
     MVSSDFENEK QPDVVQVLTD EKNISLDDKY DYEDPKNYST NYVDDYNPKG LRRPTPQESK
     SLRRVIGNIR YSTFMLCICE FAERASYYST TGILTNYIQR RIDPDSPHGW GAPPPGSPDA
     SAGALGKGLQ AASALTNLLT FLAYVFPLIG GYLGDSTIGR WKAIQWGVFF GFVAHLFFIF
     ASIPQAIENA NAGLGLCVIA IITLSAGSGL MKPNLLPLVL DQYPEERDMV KVLPTGESII
     LDREKSLSRI TNVFYLAINI GAFLQIATSY CERRVGFWLA FFVPMILYII VPIFLFIVKP
     KLKIKPPQGQ VMTNVVKILA VLFSGNFIKR LWNGTFWDHA RPSHMEARGT IYYNSKKKSA
     ITWSDQWILD IKQTFDSCKI FLYYIIFNLA DSGLGSVETS LIGAMKLDGV PNDLFNNFNP
     LTIIILIPIL EYGLYPLLNK FKIDFKPIWR ICFGFVVCSF SQIAGFVLQK QVYEQSPCGY
     YATNCDSPAP ITAWKASSLF ILAAAGECWA YTTAYELAYT RSPPALKSLV YALFLVMSAF
     SAALSLAITP ALKDPNLHWV FLAIGLAGFL CAIVMLAQFW NLDKWMENET NERERLDREE
     EEEANRGIHD VDHPIEAIVS IKS