PTR4_ARATH
ID PTR4_ARATH Reviewed; 586 AA.
AC Q9FNL8;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Protein NRT1/ PTR FAMILY 5.3;
DE Short=AtNPF5.3;
DE AltName: Full=Peptide transporter PTR3-B;
GN Name=NPF5.3; Synonyms=PTR3-B; OrderedLocusNames=At5g46040;
GN ORFNames=MCL19.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT features of the regions of 1,044,062 bp covered by thirteen physically
RT assigned P1 clones.";
RL DNA Res. 4:291-300(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP TISSUE SPECIFICITY, AND GENE FAMILY.
RX PubMed=17481610; DOI=10.1016/j.febslet.2007.04.047;
RA Tsay Y.F., Chiu C.C., Tsai C.B., Ho C.H., Hsu P.K.;
RT "Nitrate transporters and peptide transporters.";
RL FEBS Lett. 581:2290-2300(2007).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=24055139; DOI=10.1016/j.tplants.2013.08.008;
RA Leran S., Varala K., Boyer J.C., Chiurazzi M., Crawford N.,
RA Daniel-Vedele F., David L., Dickstein R., Fernandez E., Forde B.,
RA Gassmann W., Geiger D., Gojon A., Gong J.M., Halkier B.A., Harris J.M.,
RA Hedrich R., Limami A.M., Rentsch D., Seo M., Tsay Y.F., Zhang M.,
RA Coruzzi G., Lacombe B.;
RT "A unified nomenclature of NITRATE TRANSPORTER 1/PEPTIDE TRANSPORTER family
RT members in plants.";
RL Trends Plant Sci. 19:5-9(2014).
CC -!- FUNCTION: Peptide transporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in roots and siliques.
CC {ECO:0000269|PubMed:17481610}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Proton-
CC dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
CC {ECO:0000305}.
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DR EMBL; AB006698; BAB08249.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95331.1; -; Genomic_DNA.
DR RefSeq; NP_199416.1; NM_123972.1.
DR AlphaFoldDB; Q9FNL8; -.
DR SMR; Q9FNL8; -.
DR STRING; 3702.AT5G46040.1; -.
DR PaxDb; Q9FNL8; -.
DR PRIDE; Q9FNL8; -.
DR ProteomicsDB; 224836; -.
DR EnsemblPlants; AT5G46040.1; AT5G46040.1; AT5G46040.
DR GeneID; 834645; -.
DR Gramene; AT5G46040.1; AT5G46040.1; AT5G46040.
DR KEGG; ath:AT5G46040; -.
DR Araport; AT5G46040; -.
DR TAIR; locus:2161428; AT5G46040.
DR eggNOG; KOG1237; Eukaryota.
DR HOGENOM; CLU_009313_4_1_1; -.
DR InParanoid; Q9FNL8; -.
DR OMA; FYEYRAD; -.
DR OrthoDB; 365203at2759; -.
DR PhylomeDB; Q9FNL8; -.
DR PRO; PR:Q9FNL8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FNL8; baseline and differential.
DR Genevisible; Q9FNL8; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0071916; F:dipeptide transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042937; F:tripeptide transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0009624; P:response to nematode; HEP:TAIR.
DR CDD; cd17417; MFS_NPF5; 1.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR044739; NRT1/PTR.
DR InterPro; IPR000109; POT_fam.
DR PANTHER; PTHR11654; PTHR11654; 1.
DR Pfam; PF00854; PTR2; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..586
FT /note="Protein NRT1/ PTR FAMILY 5.3"
FT /id="PRO_0000300101"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 189..209
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 217..237
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 334..354
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 370..390
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 408..428
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 449..469
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 492..512
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 538..558
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 586 AA; 66201 MW; A0AC12A0159595C7 CRC64;
MTVEEVGDDY TKDGTVDLRG NRVRRSQTGR WKACSFVVVY EVFERMAYYG ISSNLVIYMT
TKLHQGTVKS SNNVTNWVGT SWLTPILGAY VADAHFGRYI TFVISSAIYL LGMALLTLSV
SLPGLKPPKC STANVENCEK ASVIQLAVFF GALYTLAIGT GGTKPNISTI GADQFDEFDP
KDKIHKHSFF NWWMFSIFFG TFFATTVLVY VQDNVGWAIG YGLSTLGLAF SIFIFLLGTR
LYRHKLPMGS PFTKMARVIV ASLRKAREPM SSDSTRFYEL PPMEYASKRA FPIHSTSSLR
FLNRASLKTG STHKWRLCTI TEVEETKQML KMLPVLFVTF VPSMMLAQIM TLFIKQGTTL
DRRLTNNFSI PPASLLGFTT FSMLVSIVIY DRVFVKFMRK LTGNPRGITL LQRMGIGMIL
HILIMIIASI TERYRLKVAA EHGLTHQTAV PIPLSIFTLL PQYVLMGLAD AFIEIAKLEF
FYDQAPESMK SLGTSYTSTS MAVGYFMSSI LLSSVSQITK KQGRGWIQNN LNESRLDNYY
MFFAVLNLLN FILFLVVIRF YEYRADVTQS ANVEQKEPNM VDNYNE
