PTR9_CAEEL
ID PTR9_CAEEL Reviewed; 844 AA.
AC Q03602;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 2.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Patched-related protein 9;
GN Name=ptr-9; ORFNames=F54G8.5;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=7906398; DOI=10.1038/368032a0;
RA Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA Wilkinson-Sproat J., Wohldman P.;
RT "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT elegans.";
RL Nature 368:32-38(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the patched family. {ECO:0000305}.
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DR EMBL; Z19155; CAA79560.3; -; Genomic_DNA.
DR PIR; S28276; S28276.
DR RefSeq; NP_499030.2; NM_066629.4.
DR AlphaFoldDB; Q03602; -.
DR SMR; Q03602; -.
DR PaxDb; Q03602; -.
DR EnsemblMetazoa; F54G8.5.1; F54G8.5.1; WBGene00004223.
DR GeneID; 191747; -.
DR KEGG; cel:CELE_F54G8.5; -.
DR UCSC; F54G8.5; c. elegans.
DR CTD; 191747; -.
DR WormBase; F54G8.5; CE37974; WBGene00004223; ptr-9.
DR eggNOG; KOG1934; Eukaryota.
DR HOGENOM; CLU_002359_2_1_1; -.
DR InParanoid; Q03602; -.
DR OMA; FRNDIRF; -.
DR OrthoDB; 210960at2759; -.
DR PhylomeDB; Q03602; -.
DR PRO; PR:Q03602; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00004223; Expressed in embryo and 1 other tissue.
DR GO; GO:0030659; C:cytoplasmic vesicle membrane; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0006897; P:endocytosis; IBA:GO_Central.
DR GO; GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR Pfam; PF02460; Patched; 1.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..844
FT /note="Patched-related protein 9"
FT /id="PRO_0000205974"
FT DOMAIN 264..421
FT /note="SSD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00199"
SQ SEQUENCE 844 AA; 96013 MW; 08072365541BD61F CRC64;
MKSLNFQSVV SQFFEYESTV VVRWPLPFII IPPLLTFSIV TLTVTNFHLN VTNDTLQVFL
PDDMRSLRDL KELLRLFPPR DAQRDTYSIF GSKFVYTVIE DDSSDGNILS SSGIQRMSKL
HKFVMGLETS LGDNVASNCL RNKDDEACTM HPIAFALEDT TPEFAIQFLL RYPNLKFGDF
VIDNAMVFGD VRIEPKSQDR DGNSPIRSSK AVRMTYILES SESTERWIDL FLSAIPRYKE
TNSTIFWSSS KSLAKEMERN GELLIPWMPW TSLVLVVFCM FACSSLNIVK SQPFIGFFAM
FNATMATIAS TSLLLYLQYP FLPLVFIMPF LVVSIGTDNM FLMLKSWRMT KKSSNEEQRY
IHALTESAAS LFLTSLTDGL SFAIGSISDF HAVRVFCTYC AMAILFMFLF QVTFFNAVMS
LCCRREVSGK HPVFCCYEIT PPEETQVLEK QSNFDFSSIV AKHLFKILNP LPSRIGVFFI
FLAYLFISIH FAIGLPLGLD LKLLAPDDSY VSKELEAQER LFADYGGFCF ALVRAENISL
KDPMVRRNLI GLYRDLGGSE YSSPSEFWLD PFEKKNRGKK YSESDFSDEL HTFLAKEPHL
KFRNDIRFTM MGKIEAMKMM FRVRKLGKDN DAPRAEYMRK VMENSQFNGF VYDTSFLLVD
QQMTTVYNVI VDVVSAILTM LSICVLMVPR PVSAMCIAFA ILSVNIGVIG ALAATNTRLD
IISMITIVMS VGFSVDYVTH TTFHFVIQRD NRLEKCLLVM TEPILQSALS TAIGVSLLSF
VHSYIVRTFV NTVFFVVGLG ILHGLIFLPV LLDTIVPDSE YMVPYEPQHE DEENPNHYED
LYGL